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Genetic loci associated with natural variation in hypoxia tolerance in the copepod Tigriopus californicus revealed by bulked segregant analysis
Abstract The copepod Tigriopus californicus is among crustaceans that have recently been shown to have lost key genes encoding the master regulators of the hypoxia-inducible factor (HIF) pathway, thought to be essential for oxygen homeostasis in animals. This species inhabits supralittoral pools that impart hours of hypoxic stress daily, frequently reaching anoxia. Despite lacking the canonical HIF transcription factor, T.
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