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Fidel Nicolás Lolo

As seen in: Cell Reports
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Articles

PERK-dependent reciprocal crosstalk between ER and non-centrosomal microtubules coordinates ER architecture and cell shape

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By Miguel Sanchez-Alvarez, Heba Sailem, Mauro Català-Montoro, Mar Arias-Garcia, Juan Lopez, Juan López, Jesús Vázquez Verified, Chris Bakal, Fidel Nicolás Lolo, Giulio Fulgoni, Patricia Pascual-Vargas, Lucía Agüera
| Cell Reports Verified
Keywords endoplasmic reticulum integrated stress response EIF2AK3/PERK non-centrosomal microtubules cell polarity Research topic(s) CP: Cell biology Introduction The eukaryotic endoplasmic reticulum (ER) serves several essential functions, including calcium and redox homeostasis, complex lipid metabolism, and the maturation and assisted folding of ∼30% of the proteome.1 ER membrane subdomains can adopt discrete shapes (including ER “tubules” [peripheral, reticular tubes of ER with rather low...
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