Fion Shiau on Muck Rack

Fion Shiau

As seen in: Nature, Science Magazine, Cell Press
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Articles

In-Depth characterization of the shared genetic architecture of suicide attempts with other major psychiatric disorders - Translational Psychiatry

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By Min Kim, Sophia Gunn, Dong Wang, Fion Shiau, Pedro Lazcano, J. Mann, TJ Singh
| Nature
Abstract Suicide is a significant public health problem that usually co-occurs with major psychiatric disorders. Suicidal behaviors have heritability of 30–50%, and the largest genome-wide association studies identified 12 loci linked to suicide attempts (SA). These findings indicate shared genetic architecture among SA and psychiatric disorders.
Open in Who Shared Issue with article?

Single-cell transcriptomics of ventral forebrain progenitors identifies Evf2 enhancer lncRNA-enhancer gene guidance through direct RNA binding and RNP recruitment domains | Nature Communications

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By Edward B. Li, Abhijit Chakraborty, Fion Shiau, Jack Kessler, Ferhat Ay, Brian Clark
| Nature
Abstract During mouse embryonic brain development, the Evf2 ultraconserved enhancer (UCE) lncRNA guides the Dlx5/6UCE to ~129 sites across chr6. However, previous work identified only 4 transcriptionally regulated targets associated with Evf2-Dlx5/6UCE-gene guidance, raising questions about the significance of Evf2-regulated Dlx5/6UCE-gene interactions.
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Atoh7-independent specification of retinal ganglion cell identity

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By Brian Clark, Qing Shi, Fion Shiau, Justin Brodie-Kommit
| Science Magazine
Abstract Retinal ganglion cells (RGCs) relay visual information from the eye to the brain. RGCs are the first cell type generated during retinal neurogenesis.
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