Fionä Caratis on Muck Rack

Fionä Caratis

As seen in: PLOS ONE
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Articles

Differential expression and modulation of EBI2 and 7α,25-OHC synthesizing (CH25H, CYP7B1) and degrading (HSD3B7) enzymes in mouse and human brain vascular cells

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By Fionä Caratis, Bartosz Karaszewski, Ilona Klejbor, Collegium Medicum
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Caratis F, Karaszewski B, Klejbor I, Furihata T, Rutkowska A (2025) Differential expression and modulation of EBI2 and 7α,25-OHC synthesizing (CH25H, CYP7B1) and degrading (HSD3B7) enzymes in mouse and human brain vascular cells. PLoS ONE 20(2): e0318822.
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Systemic inflammation modulates the levels of EBI2 and 7α,25-OHC synthesizing (CH25H, CYP7B1) and degrading (HSD3B7) enzymes in brain microvascular cells

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By Fionä Caratis, Bartosz Karaszewski, Ilona Klejbor, Tomomi Furihata
| biorxiv.org
Abstract The endogenous ligand for the EBI2 receptor, oxysterol 7α,25OHC, crucial for immune responses, is finely regulated by CH25H, CYP7B1 and HSD3B7 enzymes. Lymphoid stromal cells and follicular dendritic cells within T cell follicles maintain a gradient of 7α,25OHC, with stromal cells increasing and dendritic cells decreasing its concentration. This gradient is pivotal for proper B cell positioning in lymphoid tissue.
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The proton-sensing receptors TDAG8 and GPR4 are differentially expressed in human and mouse oligodendrocytes: Exploring their role in neuroinflammation and multiple sclerosis

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By Fionä Caratis, Mikołaj Opiełka, Martin Hausmann, Maria Velasco-Estevez
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Caratis F, Opiełka M, Hausmann M, Velasco-Estevez M, Rojek B, de Vallière C, et al. (2024) The proton-sensing receptors TDAG8 and GPR4 are differentially expressed in human and mouse oligodendrocytes: Exploring their role in neuroinflammation and multiple sclerosis. PLoS ONE 19(3): e0283060.
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