Fisun Vural

You are already at the latest version Background and Objectives: The aim of the present study was to explore the histopathological effects and tissue Vascular Endothelial Growth Factor (VEGF) levels of filgrastim and hyaluronic acid treatment in a rat model with experimentally induced Asherman Syndrome. In this study, 26 female Sprague Dawley rats were used. First, a rat model of Asherman Syndrome model was established in 2 rats. The remaining rats were randomly divided into three groups.

1. Introduction Intrauterine adhesions (IUA), also known as Asherman Syndrome (AS), involve the formation of scar tissue within the uterine cavity. This condition was first described by Heinrich Fritsch in 1894, and the term “Asherman Syndrome” was later coined by Josef Asherman in 1948 [1,2]. Since then, numerous cases and various treatment protocols have been reported.