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Flurin Cathomas

As seen in: Nature, BioRxiv, Cell Press, JNeurosci, medRxiv, The Journal of Clinical Psychiatry, Biological Psychiatry
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Articles

Major depressive disorder shares systemic immune signatures and potential therapeutic targets with inflammatory skin diseases - Molecular Psychiatry

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By Helen Y He, Flurin Cathomas, Lyonna F. Parise, Eden David, Mina M. Rizk, Kelly Hawkins, Scott Russo, Emma Guttman, James W Murrough, Elizabeth Karpman
| Nature Verified
Abstract Major depressive disorder (MDD) is a prevalent neuropsychiatric disorder associated with significant morbidity and mortality. Increasing evidence suggests that a subset of MDD patients exhibit a dysregulated immune system. However, few clinical studies have tested the efficacy of anti-inflammatory drugs in reducing symptoms of depression.
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Immunity in rodent models of stress

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By Scott Russo, Flurin Cathomas, Sebastian Hachenberg
| Biological Psychiatry Verified
Key Words Stress Animal Models Major Depressive Disorder Microglia Blood-Brain Barrier Peripheral Immune System Introduction Our bodies constantly adapt to external conditions, and appropriate responses to environmental changes are essential for survival. This is particularly relevant when we encounter threats, during which the autonomic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis orchestrate the body’s reaction to mediate the acute “fight-or-flight” response (1).
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Major-depressive-disorder-associated dysregulation of ZBTB7A in orbitofrontal cortex promotes astrocyte-mediated stress susceptibility

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By Sasha L. Fulton, Jaroslav Bendl, Giuseppina Di Salvo, John F. Fullard, Amni Al-Kachak, Ashley E. Lepack, Andrew Stewart, Sumnima Singh, Ryan Bastle, Mads E. Hauberg, Amanda K. Fakira, Vishwendra Patel, Min Chen, Romain Durand-de Cuttoli, Isabel Gameiro-Ros, Flurin Cathomas, Aarthi Ramakrishnan, Kelly Gleason, Li Shen, Carol Tamminga, Ana Milosevic, Scott Russo, Filip K. Swirski, Paul A Slesinger, Ishmail Abdus-Saboor, Robert Blitzer, Panos Roussos, Ian Maze
| Cell Press Verified
STAR★Methods REAGENT or RESOURCESOURCEIDENTIFIER Antibodies Rabbit anti-ZBTB7A (human) Abcam Cat# ab175918; RRID: AB_3696416 Rabbit anti-ZBTB7A (mouse) Abcam Cat# ab106592; RRID: AB_10866676 Rabbit anti-GAPDH Abcam Cat# ab9485; RRID: AB_307275 Rabbit anti-H3.3 Abcam Cat# ab1791; RRID: AB_302613 Goat Anti-Rabbit-HRP Bio-Rad Cat# 170-6515; RRID: AB_11125142 Chicken anti-GFAP Thermo Scientific Cat# PA1-10004; RRID: AB_1074620 Mouse anti-NeuN Millipore Cat# MAB377; RRID: AB_2298772 Goat...
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