Francesca Ferrante on Muck Rack

Francesca Ferrante

Amsterdam
As seen in: Nature, Wiley Online Library, MDPI, Vogue Italia, Her Campus, GQ Italia, Future Medicine, Made in PGH
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Articles

Small molecule-mediated activation of Notch signal transduction

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By Benedetto Daniele Giaimo, Qingwen Yang, Martin Diener, Tobias Friedrich, Francesca Ferrante, Jan Dreute, M. Lienhard Schmitz, Astrid Weiss, Pierfrancesco Polo, Matthias Lauth, Bernd M. Gahr, Steffen Just, Marek Bartkuhn, Franz Oswald, Tilman Borggrefe, Subhamita Dey, Iva Katharina Zöllner, Hina Zarrin, Jasmin Ballout
| Nature Verified
Abstract The Notch signaling pathway is pivotal in regulating cell differentiation, stem cell maintenance and oncogenesis. While several Notch inhibitors have been developed, effective small molecule activators are scarce. Here, we identify a small molecule that robustly activates Notch signaling, leading to significant upregulation of Notch target genes in several human cell lines and in Danio rerio embryos.
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TTV Species Diversity as a Novel Biomarker of Immune Dysregulation in Aging

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By Federica Novazzi, Pietro Giorgio Spezia, Francesca Ferrante, Angelo Genoni
| Wiley Online Library Verified
1 Introduction Anelloviruses, which constitute one of the most prevalent components of the human virome, have the potential to serve as a reliable, accurate, universal, and noninvasive biomarker for evaluating immune system responsiveness. This is particularly significant in geriatric clinical contexts, such as assessing frail elderly patients [1-3]. Currently, there is no universal biomarker to quantify immune system function.
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Diagnostics | Free Full-Text | Combined Use of Phenotypic Screening and of a Novel Commercial Assay (REALQUALITY Carba-Screen) for the Rapid Molecular Detection of Carbapenemases: A Single-Center Experience

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By Federica Novazzi, Gabriele Arcari, Francesca Ferrante, Sara Boutahar
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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