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Frederik Barkhof on Muck Rack

Frederik Barkhof

As seen in: Nature, Wiley Online Library, Memory Studies, Journal of Neurology, Neurosurgery and Psychiatry, SAGE Publishing, Alzheimer's Research and Therapy, JAMA (The Journal of the American Medical Association), BioRxiv, The Lancet, Neurology Journal and
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Articles

AMYPAD-PNHS: A Pan-European, Multi-Site & Multimodal MRI Dataset of Older Adults Without Dementia

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By Leonard Pieperhoff, Mario Tranfa, Prithvi Arunachalam, Carole H Sudre, Beatriz Padrela, Federico Masserini, Stefano Caneva, Giuseppe Pontillo, Emma S. Luckett, Craig Ritchie, Mercè Boada, Marta Marquié, Wiesje van der Flier, Rik Vandenberghe, Lisa Quenon, Bernard J. Hanseeuw, Pablo Martínez-Lage, Pierre Payoux, Anouk den Braber, Pieter Jelle Visser, Michael Scholl, Giovanni B Frisoni, Andrew Stephens, Frank Jessen, Juan Domingo Gispert, Alle Meije Wink, Lyduine E. Collij, Luigi Lorenzini, Frederik Barkhof, Mathijs B. J. Dijsselhof, Henk-Jan M. M. Mutsaerts
| Nature Verified
Abstract The Amyloid Imaging to Prevent Alzheimer’s Disease Prognostic and Natural History Study (AMYPAD-PNHS) multimodal magnetic resonance imaging (MRI) dataset provides open-access longitudinal MRI data of 2759 cognitively normal or mild cognitive impairment individuals, encompassing (micro-)structural, physiological, and functional MRI sequences from 10 European parent cohorts.
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Leveraging AI for selective use of gadolinium contrast in brain MR

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By Silvia Ingala, Marko Bauer, Mathias Perslev, Kaining Sheng, Sebastian Nørgaard Llambias, Arpit Kothari, Frederik Barkhof, Michael Nielsen, Mads E. Nielsen, Akshay Pai, Ivar I. J. H. G. Wamelink, Era Dwivedi, Martin Lillholm, Bas M. M. S. Jasperse, Vera C. W. Keil
| Nature Verified
Abstract Gadolinium-based contrast agents used for brain magnetic resonance imaging improve lesion detection but are associated with acute side effects, concerns about long-term tissue deposition, and economic and environmental costs. Regulatory bodies and radiological societies therefore recommend minimizing their use where possible.
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Challenges and future directions for multiple sclerosis after the 2024 McDonald diagnostic criteria

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By Jiwon Oh, Frederik Barkhof, Amit Bar-Or, Timothy Coetzee, Massimo Filippi, Cristina Granziera, Yael Hacohen, Bernhard Hemmer, Orhun Kantarci, Ho Jin Kim, Christine Lebrun-Frenay, Xavier Montalban, Ellen M Mowry, Daniel Ontaneda, Alexandre Prat, Daniel S. Reich, Alex Rovira, Pascal Sati, Aksel Siva, Andrew Solomon, Maria Pia Sormani, Bruno Stankoff, Mar Tintoré, Anthony L. Traboulsee, Anneke van der Walt, Heinz Wiendl, Peter A Calabresi, Olga Ciccarrelli
| Nature Verified
The 2024 revision of the McDonald diagnostic criteria is an important step toward earlier and more inclusive diagnosis of multiple sclerosis. Realizing its full potential will require continued refinement of biomarkers, disease stratification and clinical trial approaches.
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