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Articles by Gabriel Moore
Filling the gap between evidence, policy and practice: are 45 and Up Study researchers planning for impact?
Aim: To improve health outcomes, policy and practice decisions should be guided by relevant and timely evidence. High-quality, large-scale population data could play an essential role in supporting evidence-based decision making. The 45 and Up Study is a long-term, large-scale cohort study with more 250 000 participants aged 45 years and over from New South Wales (NSW), Australia. Data collected by the Study is accessible to researchers, government and non-governmental bodies.
A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance
Highlights • SCH-79797 kills Gram-negative and Gram-positive bacteria with undetectable resistance • It works by simultaneously targeting folate metabolism and membrane integrity • SCH’s dual-targeting is synergistic, but only when on the same chemical scaffold • Irresistin-16, an SCH derivative, effectively treats mouse N. gonorrhoeae infection Summary The rise of antibiotic resistance and declining discovery of new antibiotics has created a global health crisis.
A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance
Highlights • SCH-79797 kills Gram-negative and Gram-positive bacteria with undetectable resistance • It works by simultaneously targeting folate metabolism and membrane integrity • SCH’s dual-targeting is synergistic, but only when on the same chemical scaffold • Irresistin-16, an SCH derivative, effectively treats mouse N. gonorrhoeae infection Summary The rise of antibiotic resistance and declining discovery of new antibiotics has created a global health crisis.
Increasing the use of research in population health policies and programs: a rapid review
Introduction It is increasingly expected that population health policies and programs are informed by the best available evidence from research.
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