Gabrielle R. Barsh

Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description nmo70368-sup-0001-FigureS1.pdfPDF document, 459.5 KB Figure S1: Testing factors affecting intralitter susceptibility to valproic acid-induced neural tube defects. (A) Sex genotype of fetuses across experiments.

Highlights • Differential retinoic acid signaling levels specify vagus motor axon target choice • Hgf-Met chemoattractant signaling is required for vagus motor axon guidance • Retinoic acid drives coordinated A-P waves of hgf and met expression • The timing of Hgf-Met signaling determines vagus motor axon target choice Summary Information flow through neural circuits often requires their organization into topographic maps in which the positions of cell bodies and synaptic targets correspond.

To use the Enhanced view of this article, please enable JavaScript on in your browser and refresh the page. Online Now Article ArticleVagus Motor Neuron Topographic Map Determined by Parallel Mechanisms of hox5 Expression and Time of Axon Initiation Gabrielle R. BarshxGabrielle R.