Gadi Rennert on Muck Rack

Gadi Rennert

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Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population - Nature Communications

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By Jianxin Shi, Kouya Shiraishi, Jiyeon Choi, Tzu-Yu Chen, Juncheng Dai, Rayjean J. Hung, Wei Zheng, Baosen Zhou, Jiucun Wang, Qiuyin Cai, Yi-Long Wu, Tongwu Zhang, Zhaoming Wang, Demetrius Albanes, Min-Ho Shin, Xu-chao Zhang, Michiaki Kubo, Yoichiro Kamatani, Yohei Miyagi, Hidehito Horinouchi, Koichi Goto, Atsushi Takahashi, Megumi Hara, Yuichiro Nishida, Koichi Matsuda, Yoshinori Murakami, Kimihiro Shimizu, Yoichi Ohtaki, Tangchun Wu, Mitchell J Machiela, Yeul Hong Kim, In-Jae Oh, Jianjun Liu, Richard S. Houlston, Xifeng Wu, Adonina Tardón, Stig E Bojesen, Mattias Johansson, Heike Bickeböller, David C. Christiani, Susanne Arnold, John Field, Sanjay Shete, Lambertus A. Kiemeney, Kjell Grankvist, Mikael Johansson, Angela Cox Verified, Jian-Min Yuan, Matthew B Schabath, Zhibin Hu, Belynda D. Hicks, Chong-Jen Yu, Norie Sawada, Shengchao Li, Pan-Chyr Yang, Victoria Stevens, Christopher I. Amos, Hongbing Shen, Takashi Kohno, I-Shou Chang, Ryuji Hamamoto, Motonobu Saito, Angela Risch, Gadi Rennert, Chung-Hsing Chen, Hsiao-Han Hung, Chao Agnes Hsiung
| Nature Verified
Abstract Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study of lung adenocarcinoma of East Asian ancestry (21,658 cases and 150,676 controls; 54.5% never-smokers) and identified 12 novel susceptibility variants, bringing the total number to 28 at 25 independent loci.
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