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Gangyin Luo on Muck Rack

Gangyin Luo

As seen in: Nature, MDPI, Royal Society of Chemistry
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Articles

A compatible gravity-driven organoid perfusion (GDOP) platform for drug screening with sensitivity and toxicity process evaluation

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By Shun Wang, Xiaoliang Zhang, Linlin Lu, Huabin Jiang, Yuqiao Bai, Xiaoran Chang, Jinxian Wang, Tianhang Yang, Gangyin Luo, Houshi Ma
| Nature Verified
Abstract High-throughput experiments, unidirectional fluid replacement, real-time process monitoring, and simultaneous drug sensitivity and toxicity tests are hard to achieve on most existing tumor organoid chips. Here, we developed a gravity-driven organoid perfusion (GDOP) platform facilitating scalable throughput and supporting drug sensitivity and toxicity assessment on organoids.
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An All-in-One Microfluidic Cryopreservation System and Protocols with Gradually Increasing CPA Concentration

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By Gangyin Luo
| Royal Society of Chemistry Verified
An All-in-One Microfluidic Cryopreservation System and Protocols with Gradually Increasing CPA Concentration In regular biosample cryopreservation operations, dropwise pipetting and continuous swirling are ordinarily needed to prevent cell damages (e.g. sudden osmotic change, toxicity and dissolution heat) caused by high-concentration cryoprotectant (CPA) addition process.
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Establishment and Validation of an Integrated Microfluidic Step Emulsification Chip Supporting Droplet Digital Nucleic Acid Analysis

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By Ying Zhang, Shun Wang, Gangyin Luo, Xinbei Lv
| MDPI
3. Results and Discussion 3.1. Simulation Results of Nozzle Pressure Distribution In this study, finite element models were built of the tree-shaped and three classic nozzle distribution designs; each design had 16 nozzles. Their flow rate distributions were simulated and compared. The mass flow at the inlet was set as 0.2 μL/s, and the pressure at the nozzle outlets was set as atmospheric pressure. The cross-sections of all of the nozzles were rectangular (28 μm (h) × 150 μm (w)).
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