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Gaomin Feng on Muck Rack

Gaomin Feng

As seen in: Nature, Cell Reports, eLife
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Articles

InsP3R signaling and actomyosin-dependent mitochondrial dynamics play essential roles in mitochondrial stress-induced longevity

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By Gaomin Feng, Elizabeth M Ruark, Alexandra G Mulligan, Anthony Hoang, Li Peng, Kristopher Burkewitz, Eric K. F. Donahue, Brianne Jacquet-Cribe
| Nature Verified
Abstract Certain forms of mitochondrial impairment confer longevity, while disease-associated mitochondrial dysfunction triggers pathogenesis. The adaptive pathways that distinguish benefit from pathology remain unclear. Here we reveal that longevity induced by mitochondrial Complex I/nuo-6 mutation in C. elegans is dependent on the endoplasmic reticulum (ER) Ca2+ channel, InsP3R.
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A tRNA processing enzyme is a key regulator of the mitochondrial unfolded protein response

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By Gaomin Feng, Claudia V. Pereira, Cláudia Pereira, James P Held, Benjamin R Saunders
| eLife
Decision letter after peer review: Thank you for submitting your article "A tRNA processing enzyme is a central regulator of the mitochondrial unfolded protein response" for consideration by eLife. Your article has been reviewed by 3 peer reviewers, one of whom is a member of our Board of Reviewing Editors, and the evaluation has been overseen by David Ron as the Senior Editor. The reviewers have opted to remain anonymous.
Open in Who Shared Issue with article?

Atf-6 Regulates Lifespan through ER-Mitochondrial Calcium Homeostasis

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By Sneha Dutta, Charlotte A. Kelley, Kristopher Burkewitz, Gaomin Feng
| Cell Reports Verified
Highlights • Loss of the UPRER mediator ATF-6 in C.
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