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Gap Ryol Lee

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Articles

tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis - Nature Immunology

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By Jing Zhou, Bing Su, Youqiong Ye, Richard A. Flavell, Chengqi Yi, Yuzhang Wu, Gap Ryol Lee
| Nature Verified
Abstract Naive T cells undergo radical changes during the transition from dormant to hyperactive states upon activation, which necessitates de novo protein production via transcription and translation. However, the mechanism whereby T cells globally promote translation remains largely unknown.
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