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Bing Su

As seen in: Nature, arXiv, Future Internet, MDPI, Science Magazine, Royal Society of Chemistry, BioRxiv, Cell Reports, Cell Press, Journal of Sensors and
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Articles

CDK2-mediated phosphorylation of TRF1 S11 facilitates DNA damage repair by remodeling telomeric chromatin

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By Xiaofang Zhou, Meng Wang, Zhuohang Chen, Wei Ma, Boya Gao, Bing Su, Yi Wang, Jun Qin, Hong Zhu, Lunquan Sun, Rong Tan, Wenzhen Hu
| Nature Verified
Abstract Telomeres, coated by the shelterin complex, prevent end-to-end fusions and aberrant DNA repair, yet how telomere-binding proteins coordinate chromatin remodeling during the DNA damage response remains unclear. Here we show that the telomeric protein TRF1 is phosphorylated at serine 11 (S11) in response to DNA double-strand breaks, a modification that enhances cellular resistance to DNA damage.
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Disease-associated microglia adopt stage-specific phenotypes that regulate T cell fate and immunity in glioma

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By Jiawen Qian, Chen Wang, Yi Zhang, Yingying Zeng, Shuangyan Zhang, Fei Gao, Yiwen Zhu, Peiliang Cai, Zhongyuan Zhang, Yanan Hu, Xiaotong Yu, Benoît Kloeckner, Marco Moreira, Yuedi Wang, Bo Wang, Chujun Zhao, Dan Zhang, Xi Chen, Shang Liu, Ronghua Liu, Feifei Luo, Liang Wu, Claudia Pasqualini, Yihua Chen, Xinyan Li, Mingfang Lu, Ziyi Li, Wei Guo, Svetoslav Chakarov, Zhaoyuan Liu, Bing Su, Rui Zhao, Yiwei Chu, Florent Ginhoux, Congwen Li, Auriane Coutansais, Huangmijia Zhuang
| Cell Press Verified
Keywords microglia disease-associated microglia DAMs macrophage glioma myeloid cells microglia-T cell interaction MHC class II PD-L1 Get full text access Log in, subscribe or purchase for full access. References 1. Louis, D.N. ∙ Perry, A. ∙ Wesseling, P. ... The 2021 WHO Classification of Tumors of the Central Nervous System: a summary Neuro. Oncol. 2021; 23:1231-1251 2. Zhang, J. ∙ Mu, R. ∙ Liu, F. Advances in brain tumor therapy: from molecular diagnostics to novel treatments Sci. China Life Sci.
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Computer Science > Computation and Language

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By Jieping Ye, Bing Su, Yurou Liu
| arXiv
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
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