Garret D. Stuber on Muck Rack

Garret D. Stuber

Seattle
As seen in: Nature, Science Magazine, Cell Press
Stuber Lab at the Center for the Neurobiology of Addiction, Pain, and Emotion at the University of Washington. We study the biological basis of motivation.
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Articles

Prefrontal to ventral tegmental area dynamics drive contingency degradation

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By Madelyn M Hjort, Zoe Garrett, Adam Gordon, Ethan Ancell, Marta Trzeciak, Michael R. Bruchas, Daniela M Witten, Nicholas A. Steinmetz, Garret D. Stuber, Pei-Yun Lu
| Nature
Abstract Cognitive flexibility refers to the adaptive neural processes that adjust learned behaviours as circumstances shift, supporting optimal decision-making and behavioural control. This includes the capacity to modify specific behaviours as the contingency between cues and rewards degrades.
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Opioid-driven disruption of the septum reveals a role for neurotensin-expressing neurons in withdrawal

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By Rhiana C. Simon, Weston Fleming, Brandy A Briones, Marta Trzeciak, Pranav Senthilkumar, Kentaro Ishii, Madelyn M Hjort, Madison Martin, Koichi Hashikawa, Andrea Sanders, Sam Golden, Garret D. Stuber
| Cell Press
Keywords opioids withdrawal addiction septum behavior neurocircuits neurotensin cell type optogenetics sequencing Get full text access Log in, subscribe or purchase for full access. References 1. Koob, G.F. ∙ Le Moal, M. Drug Addiction, Dysregulation of Reward, and Allostasis Neuropsychopharmacology. 2001; 24:97-129 2. George, O. ∙ Koob, G.F. Individual differences in the neuropsychopathology of addiction Dial. Clin. Neurosci. 2017; 19:217-229 3. Welsch, L. ∙ Bailly, J. ∙ Darcq, E. ...
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Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours - Nature

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By Madison Martin, Kelsey Barcomb, Sarah Thai, Sam Golden, Garret D. Stuber, Liangcai Gu
| Nature
Abstract As the primary source of noradrenaline in the brain, the locus coeruleus (LC) regulates arousal, avoidance and stress responses1,2. However, how local neuromodulatory inputs control LC function remains unresolved.
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