Gary Frost on Muck Rack

Gary Frost

London
As seen in: Color Research & Application, Nature, Wiley, Wiley Online Library, Cambridge University Press & Assessment, Frontiers, MDPI, The Lancet, La Presse, Black Christian News Network
Head of the Nutrition and Dietetic Research Group
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Articles

A selective and augmentable butyrate-FFAR2 signal circuitry programs the cellular identity of enteroendocrine L-cells

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By Chia-Wei Cheng, Aylin Hanyaloglu, Gary Frost, Aanya Hirdaramani
| Nature Verified
Abstract Activation of free fatty acid receptor 2 (FFAR2) on enteroendocrine L-cells mediates secretion of glucagon-like peptide 1 (GLP-1) and peptide YY (PYY), key regulators of central appetite control with therapeutic relevance to obesity.
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Separating Myths From Facts About Bread and Health

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By Peter R. Shewry, Alison Lovegrove, Gary Frost, Fred Brouns
| Wiley Online Library Verified
1 Introduction Wheat accounts for about 20% of the total calories consumed globally and production continues to increase, by almost 100 million tonnes over the past decade to a current global level of about 800 million tonnes per annum (FAOSTAT 2025). This increased production reflects higher demand, particularly in countries undergoing rapid urbanisation and industrialisation, which include low and middle-income countries in Asia and Africa.
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Upper-gastrointestinal tract metabolite profile regulates glycaemic and satiety responses to meals with contrasting structure: a pilot study - Nature Metabolism

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By Mingzhu Cai, Natalia Perez-Moral, Isabel Garcia-Perez, Julien Wist, Elaine Holmes, Andres Bernal, Gary Frost
| Nature Verified
Abstract Dietary interventions to combat non-communicable diseases focus on optimizing food intake but overlook the influence of food structure. Here, we investigate how food structure influences digestion. In a randomized crossover study, ten healthy participants were fitted with nasoenteric tubes that allow simultaneous gastric and duodenal sampling, before consuming iso-nutrient chickpea meals with contrasting cellular structures. The primary outcome is gut hormone response.
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