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Gathe Kiwan on Muck Rack

Gathe Kiwan

As seen in: AHA/ASA Journals, Annals of Vascular Surgery
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Articles

Reinterventions in Patients with Claudication and Chronic Limb Threatening Ischemia

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By Alaa Mohamedali, Gathe Kiwan, Tanner I. Kim, Yawei Zhang
| Annals of Vascular Surgery Verified
ABSTRACT Objective Patients with peripheral artery disease (PAD) present with claudication or chronic limb threatening ischemia (CLTI). CLTI patients have a more advanced stage of atherosclerosis and increased comorbidities compared to claudicants, and are at an elevated risk of major amputation and mortality after lower extremity revascularization (LER). However, the frequency of reinterventions for claudication and CLTI have not been compared.
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Inhibition of T-Cells by Cyclosporine A Reduces Macrophage Accumulation to Regulate Venous Adaptive Remodeling and Increase Arteriovenous Fistula Maturation

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By Gathe Kiwan, Luis Gonzalez, Luis González, John Langford Verified, Bogdan Yatsula
| AHA/ASA Journals
Highlights During venous remodeling, T-cells preceded macrophage accumulation in the maturing arteriovenous fistulae. Inhibition of T-cells reduced macrophage accumulation in the maturing arteriovenous fistulae. Inhibition of T-cells promoted outward remodeling and reduced vascular wall thickening. T-cells regulate macrophage accumulation to regulate adaptive venous remodeling.
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Multiple Reinterventions for Claudication are Associated with Progression to Chronic Limb-Threatening Ischemia

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By Tanner I. Kim, Gathe Kiwan, Alaa Mohamedali, Yawei Zhang
| Annals of Vascular Surgery Verified
Background Claudication has a relatively benign natural history, associated with a low risk of limb loss. However, rates of progression to chronic limb-threatening ischemia (CLTI) following lower extremity revascularization (LER) for claudication remain unclear. This study examines the long-term outcomes and risk factors associated with progression to CLTI after LER for claudication.
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