Gemechu Sembeta on Muck Rack

Gemechu Sembeta

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Nanoengineered PEG/acrylic acid smart hydrogels for controlled oxaliplatin delivery and enhanced biocompatibility

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By Kashif Barkat, Mahmood Ahmad, Syed Faisal Badshah, Irfan Anjum, Ayesha Umar, Nasir Ali, Muhammad Shahab, Ahmad Mohammad Salamatullah, Hafiz Arfat Idrees, Gemechu Sembeta, Mohamed Hefnawy
| Nature Verified
Abstract The current study was based on the preparation of pH-sensitive chemically cross-linked polyethylene glycol-co-poly(acrylic acid) PEGA 8000 Smart gels for colon targeting of Oxaliplatin (OXP). PEG 8000-based Smart gels were fabricated by the free radical polymerization technique. PEG 8000 was cross-linked with acrylic acid (AA) in an aqueous medium. Ammonium persulphate (APS) and ethylene glycol dimethacrylate (EGDMA) were used as initiator and cross-linker, respectively.
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