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Kashif Barkat

As seen in: Nature, Wiley Online Library, MDPI, SAGE Publishing, Canadian Journal of Infectious Diseases & Medical Microbiology
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Articles

Nanoengineered PEG/acrylic acid smart hydrogels for controlled oxaliplatin delivery and enhanced biocompatibility

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By Kashif Barkat, Mahmood Ahmad, Syed Faisal Badshah, Irfan Anjum, Ayesha Umar, Nasir Ali, Muhammad Shahab, Ahmad Mohammad Salamatullah, Hafiz Arfat Idrees, Gemechu Sembeta, Mohamed Hefnawy
| Nature Verified
Abstract The current study was based on the preparation of pH-sensitive chemically cross-linked polyethylene glycol-co-poly(acrylic acid) PEGA 8000 Smart gels for colon targeting of Oxaliplatin (OXP). PEG 8000-based Smart gels were fabricated by the free radical polymerization technique. PEG 8000 was cross-linked with acrylic acid (AA) in an aqueous medium. Ammonium persulphate (APS) and ethylene glycol dimethacrylate (EGDMA) were used as initiator and cross-linker, respectively.
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Innovative Self Nano‐Emulsifying Drug Delivery Systems for Peptic Ulcer Therapy: A Review

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By Syed Hassan Mujtaba, Rabia Arshad, Kashif Barkat, Waqar Aman
| Wiley Online Library Verified
1 Introduction Helicobacter pylori (H. pylori), a highly prevalent pathogens, is recognized to colonize over half of the world's population.[1] H. pylori is a common helical Gram-negative, noninvasive, microaerophilic spiral bacterium that was successfully grown in 1983 by Marshall and Warren while analyzing biopsy samples of individuals with gastritis.[1, 2] It causes stomach problems such as peptic ulcers (PUD), chronic atrophic gastritis, and gastric cancer.[3] H.
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Oxaliplatin‐loaded crosslinked polymeric network of chondroitin sulfate‐co‐poly(methacrylic acid) for colorectal cancer: Its toxicological evaluation

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By Kashif Barkat, Mahmood Ahmad, Muhammad Usman Minhas, Ikrima Khalid
| Wiley Online Library Verified
Supporting Information Additional Supporting Information may be found in the online version of this article Filename Description app45312-sup-0001-suppinfo1.pdf308.3 KB Supporting Information REFERENCES 1 ; ; ; ; ; ; J. CA Cancer J. Clin. 2008, 58, 71. 2 Cancer Treat. Rev. 2008, 34, S1. 3 ; ; Int. J. Pharm. 2002, 235, 1. 4 ; ; ; Carbohydr. Polym. 2010, 81, 372. 5 ; ; ; ; Macromol. Rapid Commun. 2014, 35, 442. 6 ; ; JPSI 2012, 1, 6. 7 ; ; ; Eur. J. Pharm. Biopharm. 2000, 50, 27. 8 ; ; ; Res. Pharm. Sci. 2015, 10, 1.
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