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Articles by George Yip
AI Adoption Is Testing Modular Firms
SKIP TO CONTENT Organizations have spent decades becoming more modular, breaking themselves into agile teams, business units, and platforms to improve flexibility and speed. But many are discovering a new... For more than two decades, modularity has been one of the dominant design principles for complex organizations. The logic is elegant: Decompose the firm into independent units with clear interfaces, and you gain flexibility, speed, and scalability.
DP103 as a critical modulator of Wnt signaling and cancer stemness: implications for precision treatment in triple negative breast cancer
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Abstract Triple-negative breast cancer (TNBC) is a clinically aggressive subtype lacking targeted therapies, often characterized by hyperactivation of the Wnt/β-catenin signaling pathway and an enriched population of cancer stem cells (CSCs). Here, we identify the DEAD-box RNA helicase DP103 as a novel modulator of Wnt/β-catenin signaling in TNBC, acting independently of its canonical helicase function.
By Wanpei Cai, Sebastian Pohl, Xianning Lai, Vivien Koh, Haoran Ma, Mark Agostino, Amudha Deivasigamani, Yi Yuan, Tuan Zea Tan, Jianxiang Chen, San Hue Hua, Shiyuan Guo, Janet Teng, Jas Min Chin, Young Lee, Madhu Kanchi, Karthik Ramesh, Yu Keung Mok, Ruby Yun-Ju Huang, Jayantha Gunaratne, Melissa Jane Fullwood, George Yip, Gautam Sethi, Jeremy P. Blaydes, Kam Man Hui, Jit Kong Cheong, Nicholas S. Tolwinski, Wei Peng Yong, Patrick Tan, Kevin Myant, Alan Prem Kumar, Catharine Shi-Yun Low, Nawat Bunnag, Jahnavi Suresh, Muthukumar Rajasekaran, Celestial T. Yap, Peter Edward Lobie, Venetia Jing-Tong Kok, Arunasalam Dharmarajan, Deog Joong Kim
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Comment les entreprises chinoises réinventent le management
Si les entreprises chinoises sont depuis longtemps encensées pour leurs prouesses en matière de fabrication, depuis peu, leur approche pragmatique de l’innovation force également le respect. L’heure est maintenant venue d’admettre qu’elles réinventent aussi le rôle du management en déployant ce que nous appelons l’« autonomie guidée augmentée grâce au digital » ou « digital enhanced directed autonomy » (Deda), en anglais. Partager
Chinese companies are reinventing management. Here are some tips for your business
By Mark J. Greeven, Katherine Xin and George S. Yip Chinese companies have long been acclaimed for their manufacturing prowess and, more recently, for their pragmatic approach to innovation. Now it’s time to recognise how they are also reinventing the role of management through an approach we call “digitally enhanced directed autonomy,” or DEDA.
How Chinese Companies Are Reinventing Management
Idea in Brief The Challenge As companies grow and become more complex, they typically become less entrepreneurial and innovative. The Traditional Response Companies in the West often try to increase frontline autonomy by reducing managerial supervision. That introduces redundancy and poor coordination. The Breakthrough Chinese companies deploy digital platforms to give employees access to shared corporate resources and capabilities.
Theranostic Applications of Glycosaminoglycans in Metastatic Renal Cell Carcinoma
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by San Hue Hua , Maximillian Viera , George W. Yip * and Boon Huat Bay * Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117594, Singapore * Authors to whom correspondence should be addressed.
(HBm+) Paradies für Händler: Chinesische Unternehmen erfinden das Kundenerlebnis neu
Fotograf Huang Qingjun ließ sich für diese Aufnahmen von Chinas boomendem Internethandel inspirieren: Er bat Menschen überall im Land, sich zusammen mit ihren Onlinekäufen ablichten zu lassen. Foto: Huang Qingjun
How Chinese Retailers Are Reinventing the Customer Journey
Idea in Brief The Challenge Retailers in Europe and the United States are far behind China in digital retail. Why It Exists China’s large and fast-growing market not only is highly digitized but also takes advantage of the massive ecosystems of Alibaba, Tencent, and others.
Good Leadership Hinges on “Organizational Intelligence”
It takes a lot to get to the top of an organization: a high IQ, emotional intelligence, technical competence, and a variety of personal characteristics, such as fortitude and resilience. Even with those qualities, many leaders fail at the top job — often because they don’t know how to get the organization to do what they want. What they lack — and what successful leaders embody, down to their marrow — is organizational intelligence.
Understanding China’s Next Wave of Innovation
Understanding China’s Next Wave of Innovation Global, Innovation, Global Strategy, R&D, Business Models Three types of emerging innovators in China are making it increasingly difficult for Western multinationals to compete. advertisement Image courtesy of Carolyn Ann Geason In recent years, a handful of Chinese companies have emerged as global innovators and have garnered a lot of attention.
Understanding China’s Next Wave of Innovation
Hello visitor. You get to see one FREE ARTICLE. To enjoy more articles like this one sign in, or create an account. Understanding China’s Next Wave of Innovation Global, Innovation, Global Strategy, R&D, Business Models Three types of emerging innovators in China are making it increasingly difficult for Western multinationals to compete.
The Golden Passport: Misunderstanding MBAs & HBS
Duff McDonald’s new book, The Golden Passport, is receiving much publicity for its blaming of Harvard Business School for most of the wrongs of American capitalism. I commend McDonald on his detailed history of HBS, much of which I recognize. But I criticize him for drawing mostly wrong conclusions.
Microsoft Starts Up
A version of this article appeared in the Spring 2017 issue of strategy+business. At the Microsoft Accelerator in Beijing, engineers are developing new technologies that could transform industries as diverse as automobiles, mobile telephony, and e-commerce. They are doing so under Microsoft’s wing, housed within the company’s Asia-Pacific R&D facility.
Engaging With Startups in Emerging Markets
For large global companies, forging effective partnerships with high-potential startups is easier said than done. The very traits that make such startups potentially complementary as partners also make it difficult for large companies to engage with them in the first place.
5 Strategy Lessons Companies Can Learn From China
How should companies exploit the unique characteristics of China? We propose five major lessons that companies should learn from China and implement as strategies.
Prognostic significance of Claudin 12 in estrogen receptor-negative breast cancer
Aims Altered expression of the Claudin (CLDN) superfamily of tight junction proteins has been reported in breast cancer. The aim of this study was to examine the immunohistochemical expression of CLDN 12 and its prognostic significance in breast cancer tissues. Methods Immunohistochemical expression of CLDN 12 was performed on tissue microarrays consisting of 232 cases of breast carcinoma and correlated with clinicopathological features as well as survival of the patients with breast cancer.
The Next Innovation Opportunity in China
A version of this article appeared in the Autumn 2015 issue of strategy+business. Just 15 years ago, China was home to 200 foreign-run R&D centers. Today, multinationals operate more than 1,500 innovation facilities throughout the country — and this number is poised to increase 20 percent by 2018 (see exhibit). But this trend involves more than sheer presence.
5 Ways To Protect Your Intellectual Property In China
Copycat China is notorious. Many Western companies hesitate to enter China or to bring in technology, because of valid concerns about loss of intellectual property. This concern is even greater when it comes to innovating or conducting R&D in China. But there is encouraging news.
The 'Three Phases' Of Chinese Innovation
In the space of less than four decades Chinese companies have moved from outright imitation to pure business innovation , in parallel with and contributing to the country’s extraordinary growth. The ‘three phases’ of this shift, while not strictly sequential, provide a narrative of relentless refinement of China’s innovative capacity.
Japan's Coming Competitive Renaissance
Guided by the ancient philosophy of bushido, a new generation of companies is set to emerge on the global scene. (originally published by Booz & Company) Illustration by Christoph Niemann For nearly a decade, the industrialized world’s attention has focused on the ailments of its second largest economy: Japan.
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