Gerry Amor Camer

You are already at the latest version Background: Comparative proteome analysis can reveal functional conservation and divergence among orthologous proteins, with important implications for pharmacology and toxicology. Protein language models (PLMs) may capture sequence-derived functional relationships beyond conventional alignment metrics.

Researchers can construct large-scale biological hypotheses that include many gene interactions by analyzing large-scale DNA sequence information [1–8]. To test a biological hypothesis, natural or artificially generated mutant organisms have been used. However, as more efficient methods are developed, construction of DNA as an entity from a designed sequence – for instance, DNA synthesis technology – has begun to be used in engineering and biology [9–11].