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Gezi Chen

As seen in: Nature, MDPI
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Articles

Astrocytic EAAT1 suppression by EV-ACLY underlies glutamate imbalance and cognitive impairment in POCD

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By Zheng Qi, Yingying Zhao, Gezi Chen, Bin Cao, Yu An Su, Jian-Jun Yang, Qinghe Xing
| Nature Verified
Abstract Postoperative cognitive dysfunction (POCD) is common in older surgical patients, yet its mechanistic underpinnings remain incompletely defined. Building on the premise that immune-cell metabolism shapes inflammatory signaling, we investigated whether microglia export metabolic instructions through extracellular vesicles (EVs) to remodel astrocytic function.
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Sustainability | Free Full-Text | The Impact of Carbon Emissions Trading on the Total Factor Productivity of China’s Electric Power Enterprises-An Empirical Analysis Based on the Differences-in-Differences Model

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By Gezi Chen, Zhenhua Hu, Ailan Xu, Shijin Xiang
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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miR-23a-3p increases endometrial receptivity via CUL3 during embryo implantation

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By Kai Huang, Linli Hu, Gezi Chen, Wenqian Fan
| bioscientifica.com
A receptive endometrium is required in a successful embryo implantation. The ubiquitination-induced β-catenin degradation is related to the implantation failure.This study aimed to elucidate whether miR-23a-3p regulates endometrial receptivity via the modulation of β-catenin ubiquitination.The expressions of miR-23a-3p and CUL3 were detected in endometrial epithelial cells (EECs) isolated from pregnant mice and in hormone-induced EEC-like Ishikawa cells.
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