Gianluca Sbardella on Muck Rack

Gianluca Sbardella

As seen in: Nature, Wiley Online Library, MDPI, ACS Publications, The Journal of Biological Chemistry
Professor at @UniSalerno, Past President of @DCFSCI and Secretary of the @EuroMedChem EC. Epigenetic Medicinal Chemistry and Chemical Biology.
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Articles

Dynamic epigenetic regulation of BCLAF1 splicing in acute myeloid leukemia

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By Gregorio Favale, Nunzio Del Gaudio, Vincenzo Carafa, Tommaso De Marchi, Dante Rotili, Sergio Valente, Antonello Mai, Gianluca Sbardella, Lucia Altucci, Carmela Dell’Aversana, Giulia Sgueglia, Crescenzo Massaro, Annamaria Muro, Ida Lettiero, Erika D’Agostino, Nicla Simonelli, Mariacarla De Simone
| Nature Verified
Abstract Dysregulation of alternative splicing is increasingly associated with cancer development and tumor progression. BCL2-associated transcription factor 1 (BCLAF1) is involved in a wide range of biological processes and it is continuously being investigated due to its intricate function in tumorigenesis and drug resistance.
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Ferroptosis and Autophagy-Dependent Cell Death in Oncology Medicinal Chemistry: Call for Papers

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By Mariateresa Giustiniano, Nouri Neamati, Gianluca Sbardella, Maria Laura Bolognesi
| ACS Publications
Cite Jump to ExpandCollapse EditorialJanuary 8, 2026 Ferroptosis and Autophagy-Dependent Cell Death in Oncology Medicinal Chemistry: Call for Papers Click to copy article linkArticle link copied! Journal of Medicinal Chemistry Cite this: J. Med. Chem.
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An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors

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By Emanuele Fabbrizi, Vladimir V. Chernyshov, Francesco Fiorentino, Gianluca Sbardella
| dx.doi.org
Significance Click to copy section linkSection link copied! HIV non-nucleoside reverse transcriptase inhibitors display high potency and specificity combined with low toxicity playing a crucial role in highly active antiretroviral therapies 3,4-Dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs) are a family of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) described since 1992 Many authors around the world determined structure–activity relationships optimizing their potency up...
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