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Gene expression profile of chronic oral graft-versus-host disease

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By Viviane Almeida Sarmento, Giselle Rocha Pinto, Vitor Antonio Fortuna, Rogério Reis Conceição
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Loading metrics Open Access Peer-reviewed Research Article Abstract Among the complications observed after allogeneic hematopoietic stem cell transplantation, graft-versus-host disease (GVHD) is the primary cause of post-transplant mortality. The oral cavity is the second most affected organ target in chronic GVHD. Tissue damage results from the upregulation of inflammatory mediators, which play a critical role in the immunopathogenesis of the disease.
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