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Giulia Gambarelli

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Articles

HELLS: the transcriptional sentinel

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By Selene Mallia, Giulia Gambarelli, Alessia Ciarrocchi, Valentina Fragliasso
| Cell Press Verified
Keywords transcription genome integrity chromatin remodeler R-loop transcriptional factors HELLS meets transcription Genome integrity is constantly threatened by the execution of its functions. Processes such as transcription, replication, and DNA repair often coexist within the same genomic regions, causing tensions in DNA [1]. This favors the emergence of breaks or lesions.
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