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Glycotechnology Group

As seen in: The Journal of Biological Chemistry
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Articles

Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors

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By Eva-Maria Krammer, Clarisse Bridot, Sonia Serna, Glycotechnology Group
| The Journal of Biological Chemistry Verified
Introduction FimH is the fimbrial adhesin from the Gram-negative Escherichia coli that accomplishes bacterial adhesion to mannosylated glycoproteins on the luminal side of epithelial linings ( 1 Hung C.S. Bouckaert J. Hung D.L. Pinkner J. Winberg C. Defusco A. Auguste C.G. Strouse R. Langermann S. Waksman G. Hultgren S.J. Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. ).
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