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Articles by Grace J Tang
Positional replication fork instability drives PARP inhibitor cytotoxicity
Abstract Although poly(ADP-ribose) polymerase inhibitors (PARPi) show promise for treating homologous recombination-deficient cancers, the observed PARPi hypersensitivity in additional genetic contexts expands their potential use in precision oncology. Yet, the DNA lesions driving PARPi-induced cytotoxicity remain poorly defined. Here we uncover distinct replication-fork lesions in specific genomic regions as key determinants of PARPi cytotoxicity.
Discovering Creative Insights in Promotional Artwork
By Grace Tang, Aneesh Vartakavi, Julija Bagdonaite, Cristina Segalin, and Vi Iyengar When members are shown a title on Netflix, the displayed artwork, trailers, and synopses are personalized. That means members see the assets that are most likely to help them make an informed choice. These assets are a critical source of information for the member to make a decision to watch, or not watch, a title.
Dosimetric Effect of Cobalt-Chrome Stabilization Hardware in Paraspinal Radiation Treatments
1. Introduction Metallic implants consisting of screw-rod systems are frequently used to reconstruct and stabilize the spine following resection of metastatic and primary spinal tumor. As the life expectancy of these patients has improved due to advances in systematic and radiation therapy [1] , an increased number of symptomatic implant failures, specifically rod fractures, have been diagnosed requiring complicated revision surgery.
linking academia, business and industry through research
Home Full-text access for editors Traffic modelling of an integrated 5G/Wi-Fi network with generally distributed user-dwell times by Shensheng Tang; John O'Rourke; Grace Tang International Journal of Wireless and Mobile Computing (IJWMC), Vol. 18, No. 3, 2020 Abstract: A traffic modelling method is proposed for an integrated 5G/Wi-Fi network with generally distributed user-dwell times.
Your face
“Welcome home, Mendel.” I greeted my DNA Scraper unit as it returned home for the day with its finds. I realized I was talking to my robots — probably a consequence of spending the past year living and working alone. I picked Mendel up from the ground, popped its lid open, and dumped the contents of the sample compartment into the desktop gene-sequencing apparatus.
Energy and Protein Supplementation Does Not Affect Protein and Amino Acid Kinetics or Pregnancy Outcomes in Underweight Indian Women
Background: In India, the prevalence of low birth weight is high in women with a low body mass index (BMI), suggesting that underweight women are not capable of providing adequate energy and protein for fetal growth.
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