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Grant D. Barish on Muck Rack

Grant D. Barish

As seen in: Nature, Cell Press
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Articles

Adipocyte NADH dehydrogenase reverses circadian and diet-induced metabolic syndrome - Nature Metabolism

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By Chelsea Hepler, Nathan Waldeck, Benjamin J. Weidemann, Biliana Marcheva, You-Jia Chen, Jacqueline Hecker, Ziming Zhu, Rino Nozawa, Joseph V. Mastroni, Anneke K. Thorne, Colleen R. Reczek, Jonathan Cedernaes, Kathryn Ramsey, Clara B Peek, Grant D. Barish, Navdeep S. Chandel, Joseph Bass
| Nature Verified
Abstract Circadian clocks are internal timing systems that enable organisms to anticipate and adapt to daily environmental changes. These rhythms arise from a transcription–translation feedback loop in which CLOCK and BMAL1 regulate the expression of thousands of genes, including their repressors PER and CRY. Disruption of circadian rhythms contributes to obesity, metabolic disease and cancer, yet how the clock maintains metabolic homeostasis remains limited.
Open in Who Shared Issue with article?

Cell Press: Cell Press

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By Amanda Allred, Jianing Wang, Cynthia Yang, Ronald Evans, Xianlin Han, Ilya Bederman, Madhavi D. Senagolage, Meredith A. Sommars, Krithika Ramachandran, Christopher R. Futtner, Yasuhiro Omura, Daniele Procissi, Grant D. Barish
| Cell Press Verified
Open in Who Shared Issue with article?
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