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Guanlei Wang on Muck Rack

Guanlei Wang

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Articles

CFTR regulates lipid metabolism by relieving adipose inflammation in obesity

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By Jingbo Chen, Mei Li, Yang Zhao, Ping Pan, Shuijie Li, Wenming Xu, Ricardo Azziz, Xiaomiao Zhao, Jieyi Du, Chuanfeng Ke, Guanlei Wang
| Nature Verified
Abstract The downregulation of the cystic fibrosis transmembrane conductance regulator (CFTR) reduces lipogenesis and alters lipid metabolism. However, the role of CFTR in inflammation regulation in adipose tissue has been unknown. This study aims to explore the role of CFTR in adipose inflammation and lipid metabolism and the underlying mechanism using both in vivo and in vitro models.
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