Guillem Mas Fiol on Muck Rack

Guillem Mas Fiol

France
As seen in: Nature
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Articles

Evaluating the early diversification of Yersinia pestis and its phylogeographic expansion over 96 years of evolution in Madagascar - Communications Biology

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By Guillem Mas Fiol, Javier Pizarro-Cerdá, David Wagner, Lovasoa Nomena Randriantseheno
| Nature Verified
Abstract Madagascar is the most plague-affected country globally, yet the phylogenetic diversity of Yersinia pestis in this country remains insufficiently characterized. In this study, we analyzed whole-genome sequences of 614 Y. pestis strains, with 141 strains newly sequenced, collected over 96 years across Madagascar. All isolates emerged in 1898 and belong to the phylogroup 1.ORI3, supporting a single introduction event to Madagascar, followed by local diversification.
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Global evolutionary patterns of Yersinia pestis and its spread into Africa

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By Frédéric Lemoine, Guillaume Bouvier, Guillem Mas Fiol, Damien Mornico
| biorxiv.org
Abstract The zoonotic pathogen Yersinia pestis, the etiologic agent of plague, has caused three major pandemics and diversified in different lineages currently established in endemic areas worldwide. However, some regions like continental Africa have been poorly covered within the global diversity and epidemiological history of this pathogen. Here, we report the whole-genome sequences of 1,124 Y.
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