Hai Minh Ta

Keywords Animals, Humans, Male, Mice, Blood-Testis Barrier, Contraceptive Agents, Male, Protein Kinase Inhibitors, Protein Serine-Threonine Kinases, Small Molecule Libraries, Testis, Contraception, Structure-Activity Relationship Abstract Men or mice with homozygous serine/threonine kinase 33 (STK33) mutations are sterile owing to defective sperm morphology and motility.

Keywords Anti-Inflammatory Agents, Non-Steroidal, Antineoplastic Agents, Contraceptive Agents, Male, DNA, Drug Discovery, Humans, Male, Nuclear Proteins, Protein Domains, Small Molecule Libraries, Structure-Activity Relationship, BET bromodomains, BRDT, DNA-encoded chemistry technology, small-molecule inhibitors Abstract BET bromodomain inhibition is therapeutic in multiple diseases; however, pan-BET inhibitors have induced significant myelosuppression and gastrointestinal toxicity, perhaps...

Research Article | Molecular Biology and Physiology Thanh Nguyen, Truc Kim, Hai Minh Ta, Won Sik Yeo, Jongkeun Choi, Pushpak Mizar, Seung Seo Lee, Taeok Bae, Akhilesh Kumar Chaurasia, Kyeong Kyu Kim Victor J. Torres, Editor DOI: 10.1128/mBio.02660-18 ABSTRACT Mannitol-1-phosphate dehydrogenase (M1PDH) is a key enzyme in Staphylococcus aureus mannitol metabolism, but its roles in pathophysiological settings have not been established.