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Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions

Nov 28, 2014 |

By Stephen Curry, Humberto Fernandes, Eoin N Leen, Hamlet Cromwell Jnr, Marc-Philipp Pfeil

| PeerJ

Noroviruses are positive-sense single-stranded RNA viruses. They encode an NS6 protease that cleaves a viral polyprotein at specific sites to produce mature viral proteins.

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Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions

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