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Articles

Alzheimer’s disease proteome-wide association study implicates adaptive immunity and identifies risk genes LILRB1 and SIRPA

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By xiaofan LI, Ruyi Zhou, Keenan A. Walker, Cassandra O. Blew, Michael Duggan, Gabriela Gomez, Shannon M. Drouin, Jingsha Chen, Jingning Zhang, Tibor Nanasi, Benoit Lehallier, Hamilton OH, Aditya Surapaneni, Morgan E. Grams, Priya Palta, Kevin Sullivan, Alexa Pichet Binette, Lang Wu, Jingjing Zhu, Hampton Leonard, Andrew Singleton, Myriam Fornage, Cassie Joynes, Jenifer Cordon, Balint File
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Mounting evidence suggests that perturbations outside the central nervous system (CNS) can modulate Alzheimer’s disease (AD).
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Global Parkinson's Genetics Program Data Release 11

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By Hampton Leonard, Dan M. Vitale, Mathew J Koretsky, Kristin Levine, Mary B. Makarious, Zih-hua Fang
| zenodo.org
In December 2025, GP2 announced the 11th data release on the Terra and the Verily® Workbench platforms in collaboration with AMP® PD. This release includes 20,842 additional genotyped participants, 17,153 additional WGS participants, and 4,232 additional clinical exomes. The genotype array (NBA) data, including locally-restricted samples, now consists of a total of 103,786 genotyped participants (46,327 PD cases, 28,857 Controls, and 28,602 ‘Other’ phenotypes).
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