Haojian Han on Muck Rack

Haojian Han

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Articles

Research and optimization of screening strategy for calcium-activated chloride channel modulators guided by electrophysiological characteristics - Scientific Reports

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By Yanyan Wang, Kai Zheng, Liu Yang, Liying Liu, Haojian Han, Shuang Chen, Zhanning Qu, Kai Qin, Wansheng Zhang, Feng Hao
| Nature Verified
Abstract Calcium-activated chloride channels (CaCCs) are essential for epithelial secretion, neuronal transmission, and smooth muscle function. Among the Anoctamin family, Anoctamin 1 (ANO1) and Anoctamin 2 (ANO2) are classical CaCCs proteins. ANO1 has been identified as a potential therapeutic target due to its involvement in diseases such as cancer and cystic fibrosis.
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