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Letter: Disease Stage and Absolute Risk in Evaluating the Branched-Chain Amino Acid to Tyrosine Ratio in Cirrhosis
Dear Editor, We read with interest the study by Utakata et al. [1]. The authors evaluated the prognostic value of the branched-chain amino acid to tyrosine ratio and its components in patients with liver cirrhosis. They showed that this marker remained independently associated with mortality after adjustment for established risk factors. These findings support the role of amino acid imbalance in risk stratification and suggest its potential clinical application.
Research and optimization of screening strategy for calcium-activated chloride channel modulators guided by electrophysiological characteristics - Scientific Reports
Abstract Calcium-activated chloride channels (CaCCs) are essential for epithelial secretion, neuronal transmission, and smooth muscle function. Among the Anoctamin family, Anoctamin 1 (ANO1) and Anoctamin 2 (ANO2) are classical CaCCs proteins. ANO1 has been identified as a potential therapeutic target due to its involvement in diseases such as cancer and cystic fibrosis.
A Dual-Layer Janus Mesh–Wedge Microgroove Surface for Spontaneous Departure and Directional Transport of Condensate
Abstract Click to copy section linkSection link copied! Sustainable dropwise condensation technology is crucial for applications in high-performance thermal management, energy conversion, and desalination. However, conventional condensation surfaces often suffer from low droplet departure efficiency and gravity dependence, limiting their practical application in advanced heat exchangers.
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