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Harvard Chan Microbiome

As seen in: Wiley Online Library, British Pharmacological Society, Frontiers, Genome Biology, Genome Medicine, JAMA (The Journal of the American Medical Association), Cell Press
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Articles

Gut Microbial Variations Associated With Proton Pump Inhibitor Use in the Boston Puerto Rican Health Study

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By Xochitl C Morgan, Harvard Chan Microbiome, Hanseul Kim, Deepika Dinesh
| British Pharmacological Society
BPRHS Boston-Puerto Rican Health Study CRP C-reactive protein DMAPP dimethylallyl diphosphate FDR false discovery rate FFQ food-frequency questionnaire GI gastrointestinal HMP Human Microbiome Project IPP isopentenyl pyrophosphate IRB Institutional Review Board MaAsLin2 Microbiome Multivariate Association with Linear Models NMDS non-metric-multidimensional-scaling OTC over the counter PERMANOVA permutational multivariate analysis of variance PPI proton pump inhibitor RF random forest ROC AUC...
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Metagenomic profiling of airborne microbial communities from aircraft filters and face masks - Microbiome

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By Harvard Chan Microbiome
| link.springer.com
Microbial composition of face masks and aircraft cabin filters We analyzed a total of 55 samples, of which 31 were Environmental (direct DNA extraction), 22 were Enrichment (cultivation prior to DNA extraction), and 2 were spike-in controls. Each specimen was divided into two portions, with one processed directly for DNA extraction (Environmental) and the other subjected to cultivation before DNA extraction (Enrichment).
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Intestinal Blastocystis is linked to healthier diets and more favorable cardiometabolic outcomes in 56,989 individuals from 32 countries

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By Elisa Piperni, Long Nguyen, Long Nguyễn, Harvard Chan Microbiome, Paolo Manghi
| Cell Press Verified
Highlights • Prevalence of Blastocystis in the gut microbiome varies across geography and lifestyle • Healthier plant-based diets are linked with higher gut Blastocystis carriage • Blastocystis-positive subjects tend to have healthier cardiometabolic profiles • Blastocystis presence increases after a diet-improving intervention program Summary Diet impacts human health, influencing body adiposity and the risk of developing cardiometabolic diseases.
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