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Hector Mesa

As seen in: Wiley Online Library, MDPI, Medscape, Cell Press, Dialnet - Universidad de La Rioja, Gastrointestinal Endoscopy Clinics of North America, Archives of Pathology

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Articles

Diagnostic Utility of Ki‐67 Index on Cell Block Material for Grading Medullary Thyroid Carcinoma

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By Tieying Hou, Hector Mesa, Bianca Puello
| Wiley Online Library Verified
1 Introduction Medullary thyroid carcinoma (MTC) is a rare endocrine tumor of the thyroid arising from calcitonin-secreting C cells. Recent studies have highlighted the prognostic significance of proliferative activity and tumor necrosis. In 2020, a three-tiered system and a two-tiered system were proposed [1, 2].
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Steroidogenic Factor 1 (SF1) Immunohistochemical Stain Is Sensitive and Specific for the Cytopathologic Identification of Intrapancreatic Ectopic Splenic Tissue

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By Adeyinka Akinsanya, Mohamed Labat Mustafa, Hector Mesa, Jessica L. Muldoon
| Wiley Online Library Verified
1 Introduction Steroidogenic factor 1 (SF1) is a nuclear transcription factor critical to the regulation of steroidogenesis and reproductive development [1]. It is predominantly expressed in steroidogenic tissues, including the adrenal cortex and gonads, where it plays a key role in the biosynthesis of steroid hormones. SF1 is also expressed in splenic endothelial cells, where it plays a crucial role in the development of the splenic venous sinuses and pulp veins.
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Developing SEMA4A-directed CAR T cells to overcome low BCMA antigen density in multiple myeloma

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By Francesco Di Meo, Francesca Albano, Yunfei Wang, Kenneth H Shain, Ariosto Silva, Hirofumi Tenshin, Xiaofei Song, Sasan Ghaffari, Hector Mesa, Ben C. Creelan, Xiaohong Zhao, Mark Meads, Paulo C. Rodriguez, Silvia Marino, Frederick Locke, Patrick Hwu, David Roodman, Jorge Mansilla-Soto, Fabiana Perna, Annamaria Cesarano, Brandon Kale, Noriyoshi Kurihara, David Jellyman
| Cell Press Verified
Keywords Multiple Myeloma CAR T cell therapy antigen density myeloma biology antibody development antigen escape relapse SEMA4A BCMA target identification Get full text access Log in, subscribe or purchase for full access. References 1. Kumar, S.K. ∙ Rajkumar, V. ∙ Kyle, R.A. ... Multiple myeloma Nat. Rev. Dis. Primers. 2017; 3, 17046 2. Costa, L.J. ∙ Brill, I.K. ∙ Omel, J. ... Recent trends in multiple myeloma incidence and survival by age, race, and ethnicity in the United States Blood Adv.
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