Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Hee Jin
Development and validation of a rapid Listeria monocytogenes loop-mediated isothermal amplification assay in soft cheese and raw pet food
Abstract Introduction: Rapid screening of Listeria monocytogenes in human and animal foods is imperative for improving laboratory efficiency and safeguarding food supply. Methods: We developed a loop-mediated isothermal amplification (LAMP) assay targeting the L. monocytogenes hlyA gene (listeriolysin O) and performed single-laboratory validation in representative human (soft cheese) and animal (raw pet food) food matrices.
Blood-based multimodal biomarker models for differentiating early-onset Alzheimer’s disease from frontotemporal dementia: a longitudinal study of early-onset dementia and family members (LEAF) study
van de Veen D, Bakker C, Peetoom K, Pijnenburg Y, Papma J, de Vugt M et al (2022) Provisional consensus on the nomenclature and operational definition of dementia at a young age, a Delphi study. Int J Geriatr Psychiatry. https://doi.org/10.1002/gps.5691 Article PubMed PubMed Central Google Scholar van de Veen D, Bakker C, Peetoom K, Pijnenburg Y, Papma JM, de Vugt M et al (2021) An integrative literature review on the nomenclature and definition of dementia at a young age.
Targeting the senescence‒autophagy axis via p16 INK4a inhibition alleviates pulmonary fibrosis
Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease for which effective therapies are lacking. While cellular senescence and autophagy have been implicated in IPF pathogenesis, the intersecting mechanisms that drive fibrosis progression remain unclear. Our patient-derived transcriptomic analysis revealed a strong association between enhanced extracellular matrix remodeling, cellular senescence, and autophagic dysfunction in IPF.
Plasma acid sphingomyelinase activity in sepsis: diagnostic utility and association with disease severity - Critical Care
Plasma acid sphingomyelinase (ASM) is a key enzyme generating ceramide, a lipid mediator implicated in inflammation, endothelial injury, and microvascular dysfunction [1, 2]. Although increased ASM activity has been described in sepsis [3, 4], its clinical relevance in relation to disease severity remains insufficiently characterized.
Plasma phosphorylated tau 217 and amyloid‑β 42/40 for amyloid risk in subgroups - Alzheimer's Research & Therapy
Participants were consecutively recruited from the Korea-Registries to Overcome dementia and Accelerate Dementia (K-ROAD) project, a multicenter nationwide initiative involving 25 tertiary-care hospitals across South Korea between 2016 and 2024, with Samsung Medical Center (SMC) serving as the core institution.
Association of serum AMH levels with the number of oocytes retrieved in adolescent and young adult women undergoing controlled ovarian stimulation for fertility preservation | Archives of Gynecology and Obstetrics
Abstract To investigate whether the number of oocytes retrieved after controlled ovarian stimulation (COS) for fertility preservation (FP) can be predicted using serum anti-Müllerian hormone (AMH) levels in adolescent and young adult (AYA) women. This is a retrospective cohort study in a large university-affiliated fertility center. AYA women aged 11 to 25 years received COS using gonadotropin-releasing hormone (GnRH) antagonist protocols for FP were enrolled.
Anti-Melanogenic Effects of Umbelliferone: In Vitro and Clinical Studies
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Nanopore Sequencing Allows Recovery of High-Quality Completely Closed Genomes of All Cronobacter Species from Powdered Infant Formula Overnight Enrichments
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Effects of perceived sleep quality on creative behavior via work engagement: the moderating role of gender - BMC Psychology
Sleep quality is defined as individuals’ satisfaction with their overall sleep experience, encompassing factors such as ease of falling asleep, sleep initiation, maintenance, duration, and mental state upon waking up [30]. Prior research has shown that high sleep quality facilitates the replenishment of personal resources, enabling individuals to more effectively meet the cognitive, emotional, and physical demands of their work [31].
Effects of risk factors on the development and mortality of early- and late-onset dementia: an 11-year longitudinal nationwide population-based cohort study in South Korea | Alzheimer's Research & Therapy | Full Text
We used the Korean National Health Insurance Service (NHIS) database, which contains primary demographic and health insurance claim data from 2002. The NHIS is a single insurer under the universal health insurance service in which all Korean citizens are enrolled. The NHIS database contains annual data on diagnoses and medications that allow us to track the incidence of dementia over time.
Mussel-inspired resilient hydrogels with strong skin adhesion and high-sensitivity for wearable device - Nano Convergence
Pectin from citrus peels (PT, galacturonic acid, ≥ 74%), dopamine hydrochloride (DA, > 98%), acrylic acid (AA, > 99%), ammonium persulfate (APS, > 98%), 1-ethyl-3-(3-(dimethylamino) propyl) carbodiimide hydrochloride (EDC, > 98%), N-hydroxysuccinimide (NHS, > 98%), N,N′-Methylenebis-(acrylamide) (MBAA, > 98%), Ferric nitrate (Fe(NO3)3·9H2O) and natural graphite oxide (GO) were purchased from Sigma Aldrich, USA. All other chemicals were purchased commercially and used without further purification.
The associations of herpes simplex virus and varicella zoster virus infection with dementia: a nationwide retrospective cohort study - Alzheimer's Research & Therapy
In this nationwide population-based study, the effects of HSV or VZV infection on dementia were comprehensively investigated. The study results showed that HSV and VZV infections were significantly associated with the increased risk of dementia independent of possible confounding factors including age, sex, depression, dyslipidemia, ischemic stroke, CHD, HTN, DM, CKD, BMI, and household income level.
Comprehensive Transcriptomic Profiling of Diverse Brain Tumor Types Uncovers Complex Structures of the Brain Tumor Microenvironment
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Distinct effects of cholesterol profile components on amyloid and vascular burdens - Alzheimer's Research & Therapy
We enrolled 1,175 non-demented participants (456 with CU and 719 with MCI) aged ≥ 45 years who underwent Aβ PET in the memory clinic at the Samsung Medical Center (Seoul, Korea) between August 2015 and August 2020. All participants underwent a comprehensive dementia examination including a standardized neuropsychological test [16], APOE genotyping, and brain magnetic resonance imaging (MRI).
Sex-specific relationship between non-alcoholic fatty liver disease and amyloid-β in cognitively unimpaired individuals
Introduction Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease (Younossi et al., 2016) that has detrimental effects on multiple extrahepatic health conditions and liver-related outcomes. NAFLD is closely associated with metabolic syndromes, including diabetes and insulin resistance and complications of metabolic syndromes such as cardiovascular diseases (Gaggini et al., 2013). Thus, NAFLD is considered a hepatic manifestation of metabolic syndrome.
Clinical effects of novel susceptibility genes for beta-amyloid: a gene-based association study in the Korean population
Introduction Aging population is growing worldwide. By 2050, the world’s population with age over 65 is anticipated to increase to approximately 1.5 billion (United Nations Department of Economic and Social Affairs, 2021). WHO reported in 2012 that about 150 million people would be impacted by dementia by 2050 (Patterson, 2018), which would subsequently increase the total costs of Alzheimer’s disease (AD), the most common cause of dementia, to over $1 trillion (Prince et al., 2015).
Mediating effects of attention problems on the link between parenting style and internet gaming disorder in adolescents
Introduction Parenting style and child and adolescent behavior Parenting style is defined as the manner in which parents rear their children (1–3). Parenting behaviors are known to be associated with adolescents’ emotional and problem behaviors (1, 2). Schaefer et al. (3) suggested two independent parenting styles of emotion and control. The emotion dimension involves parents’ emotional attitude toward the child (affection vs.
Linguistic, visuospatial, and kinematic writing characteristics in cognitively impaired patients with beta-amyloid deposition
1. Introduction Beta amyloid (Aβ) deposition is recognized as a key pathological feature of Alzheimer’s disease (AD), a degenerative disease. Aβ deposition can result in axonal injury, synaptic dysfunction, and reduction of neuronal connections and acetylcholine (Richards and Sabbagh, 2014; Walhovd et al., 2014). Aβ is deposited as plaques starting in the basal temporal and orbitofrontal neocortex, followed by deposition in the allocortex and amygdala.
Frontiers | Dementia incidence and population-attributable fraction for dementia risk factors in South Korea: A 12-year longitudinal follow-up study of a national cohort
Dementia incidence and population-attributable fraction for dementia risk factors in South Korea: A 12-year longitudinal follow-up study of a national cohort 1Samsung Medical Center, Sungkyunkwan University, Republic of Korea 2Chung-Ang University, Republic of Korea 3Seoul National University, Republic of Korea The final, formatted version of the article will be published soon.
Rethinking Cheonggye Stream Restoration Project: Is urban greening strategy socially inclusive?
Rethinking Cheonggye Stream Restoration Project: Is urban greening strategy socially inclusive?
The risk of dementia in multiple sclerosis and neuromyelitis optica spectrum disorder
Introduction Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are chronic inflammatory demyelinating diseases of the central nervous system (CNS) involving the optic nerve, spinal cord, and brain.
Multi-strain probiotics alleviate loperamide-induced constipation by adjusting the microbiome, serotonin, and short-chain fatty acids in rats
Introduction Constipation is a common gastrointestinal (GI) disorder, and its prevalence is estimated to be 16% worldwide (Forootan et al., 2018). This symptom was reported more often in women than in men and in elderly people than in young people (Faigel, 2002). Various causes of constipation are known, but it can result from intestinal obstruction, lack of exercise, low fiber intake, or personal factors (Bosaeus, 2004).
The Risk of Dementia in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder
The Risk of Dementia in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder 1College of Medicine, Gyeongsang National University, Republic of Korea 2Gyeongsang National University Changwon Hospital, Republic of Korea 3Seoul National University Bundang Hospital, Republic of Korea 4Catholic University of Korea, Republic of Korea 5Hallym University Dongtan Sacred Heart Hospital, Republic of Korea 6Samsung Medical Center, Sungkyunkwan University, Republic of Korea 7Soongsil University,...
Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease
Acta Neuropathologica Communications, Apr 2023 This is a preview of a remote PDF: https://actaneurocomms.biomedcentral.com/counter/pdf/10.1186/s40478-023-01563-4 Ali, Muhammad, Archer, Derek B., Gorijala, Priyanka, Western, Daniel, Timsina, Jigyasha, Fernández, Maria V., Wang, Ting-Chen, Satizabal, Claudia L., Yang, Qiong, Beiser, Alexa S., Wang, Ruiqi, Chen, Gengsheng, Gordon, Brian, Benzinger, Tammie L.
Gut microbiota as a potential key to modulating humoral immunogenicity of new platform COVID-19 vaccines
Signal Transduction and Targeted Therapy, May 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41392-023-01445-0.pdf Seong, Hye, Choi, Bo Kyu, Han, Young-Hee, Kim, Jun Hyoung, Gim, Jeong-An, Lim, Sooyeon, Noh, Ji Yun, Cheong, Hee Jin, Kim, Woo Joo, Song, Joon Young. , Signal Transduction and Targeted Therapy, DOI: 10.1038/s41392-023-01445-0
Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease - Acta Neuropathologica Communications
We thank all the participants and their families, as well as the involved cohorts, institutions, and their staff. The recruitment and clinical characterization of research participants at Washington University were supported by NIH P30 AG066444 (JCM), P01 AG03991 (JCM), and P01 AG026276 (JCM).
Frontiers | Mediating effects of attention problems on the link between parenting style and internet gaming disorder in adolescents Short title: Attention, parenting style, and internet gaming
Sung A. Chung1, Sujin Bae1, Hee J. Kim2, Jea-Woog Lee2, Hyunchan Hwang1 and Doug Hyun Han2* 1Chung-Ang University Hospital, Republic of Korea 2Chung-Ang University, Republic of Korea The final, formatted version of the article will be published soon.
Different effects of cardiometabolic syndrome on brain age in relation to gender and ethnicity
Alzheimer's Research & Therapy, Mar 2023 This is a preview of a remote PDF: https://alzres.biomedcentral.com/counter/pdf/10.1186/s13195-023-01215-8 Kang, Sung Hoon, Liu, Mengting, Park, Gilsoon, Kim, Sharon Y., Lee, Hyejoo, Matloff, William, Zhao, Lu, Yoo, Heejin, Kim, Jun Pyo, Jang, Hyemin, Kim, Hee Jin, Jahanshad, Neda, Oh, Kyumgmi, Koh, Seong-Beom, Na, Duk L., Gallacher, John, Gottesman, Rebecca F., Seo, Sang Won, Kim, Hosung. , Alzheimer's Research & Therapy, 2023, pp.
Different effects of cardiometabolic syndrome on brain age in relation to gender and ethnicity - Alzheimer's Research & Therapy
Study populations We enrolled CU participants aged ≥ 45 years from the Health Promotion Center of Samsung Medical Center (Seoul, Korea) who underwent a comprehensive health screening exam from September 1, 2008, to October 31, 2019. A total of 8227 eligible candidates underwent a full medical examination, which included cognitive assessment and 3.0-Tesla MRI, including high-resolution T1-weighted MRI, as part of a standard screening for dementia.
Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer’s disease - Nature Communications
Abstract Acid sphingomyelinase (ASM) has been implicated in neurodegenerative disease pathology, including Alzheimer’s disease (AD). However, the specific role of plasma ASM in promoting these pathologies is poorly understood. Herein, we explore plasma ASM as a circulating factor that accelerates neuropathological features in AD by exposing young APP/PS1 mice to the blood of mice overexpressing ASM, through parabiotic surgery.
Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma - Genome Medicine
Patient samples After written informed consent was obtained, we utilized tumor specimens of patients whose first therapeutic intervention was an open surgical resection at the Samsung Medical Center in accordance with the Institutional Review Board. Overall, 128 GBM specimens (108 primary, 19 recurrent, 1 unknown) were collected from 92 GBM patients with median age at diagnosis 57 (range 29-80) including 39 females and 53 males.
Identifying genetic variants for amyloid β in subcortical vascular cognitive impairment
Hang-Rai Kim1, Sang-Hyuk Jung2, Beomsu Kim2, Jaeho Kim3, Hyemin Jang4, Junpyo Kim5, So Yeon Kim2, Duk L Na4, Hee Jin Kim4, Kwangsik T.
The effects of imaging markers on clinical trajectory in cerebral amyloid angiopathy: a longitudinal study in a memory clinic
Alzheimer's Research & Therapy, Jan 2023 This is a preview of a remote PDF: https://alzres.biomedcentral.com/counter/pdf/10.1186/s13195-023-01161-5 Jang, Hyemin, Chun, Min Young, Kim, Hee Jin, Na, Duk L., Seo, Sang Won. , Alzheimer's Research & Therapy, 2023, pp. 1-9, Volume 15, Issue 1, DOI: 10.1186/s13195-023-01161-5
Improvement of the intestinal epithelial barrier during laxative effects of phlorotannin in loperamide-induced constipation of SD rats
Laboratory Animal Research, Jan 2023 This is a preview of a remote PDF: https://labanimres.biomedcentral.com/counter/pdf/10.1186/s42826-022-00152-1 Kim, Ji Eun, Song, Hee Jin, Choi, Yun Ju, Jin, You Jeong, Roh, Yu Jeong, Seol, Ayun, Park, So Hae, Park, Ju Min, Kang, Hyun Gu, Hwang, Dae Youn. , Laboratory Animal Research, 2023, pp. 1-11, Volume 39, Issue 1, DOI: 10.1186/s42826-022-00152-1
Blue Education Co.
Date: 2023-01-19 Category: Shopping OS: iOS Compatible: iPhone iPad Requirements: Requires iOS 13.0 or Description - Blue Education Co. . The Blue Education Co. is now available as a free download on Apple Store for both iPhone and iPad owners.The application is supporting different languages: English, Japanese, Korean, Portuguese, Simplified Chinese, Spanish, Traditional Chinese, Vietnamese. It weighs in at only 31.3 MB to download.
The effects of imaging markers on clinical trajectory in cerebral amyloid angiopathy: a longitudinal study in a memory clinic - Alzheimer's Research & Therapy
Study participants For the selection of study participants, we reviewed Neuroimaging Study Registries of patients who visited a memory clinic in Samsung Medical Center complaining of cognitive impairment. We first reviewed 5248 patients from MRI registries obtained in the memory clinic of Samsung Medical Center between July 2007 to December 2016. Since 2016, we also have developed the CAA imaging registry with compatible patients.
Case report: cerebrotendinous xanthomatosis with a novel mutation in the CYP27A1 gene mimicking behavioral variant frontotemporal dementia
Min Young Chun1, Nam Jin Heo1, Sang Won Seo1, Hyemin Jang1, Yeon-Lim Suh1, Ja-Hyun Jang1, Young-Eun Kim2, Eun-Joo Kim3, So Young Moon4, Na-Yeon Jung5, Sun Min Lee4 and Hee Jin Kim1* 1Samsung Medical Center, Sungkyunkwan University, Republic of Korea 2College of Medicine, Hanyang University, Republic of Korea 3School of Medicine, Pusan National University, Republic of Korea 4School of Medicine, Ajou University, Republic of Korea 5Pusan National University Yangsan Hospital, Republic of Korea...
Bifidobacterium-derived short chain fatty acids and indole compounds attenuate nonalcoholic fatty liver disease by modulating gut-liver axis
Sang Jun Yoon1, Jeong Seok Yu2, Byeong Hyun Min1, Haripriya Gupta1, Sung-Min Won1, Hee Jin Park1, Sang Hak Han1, Byung-Yong Kim3, Kyung Hwan Kim4, Byoung Kook Kim4, Hyunchae Joung4, Tae-Sik Park5, Young Lim Ham6, Do Yup Lee2 and Ki Tae Suk1* 1College of Medicine, Hallym University, Republic of Korea 2Seoul National University, Republic of Korea 3Other, Republic of Korea 4CKD Bio, Republic of Korea 5Gachon University, Republic of Korea 6Daewon University College, Republic of Korea...
The Microbiome in Systemic Sclerosis: Pathophysiology and Therapeutic Potential
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Suhee Kim , Hee Jin Park and Sang-Il Lee * Department of Internal Medicine and Institute of Health Science, College of Medicine, Gyeongsang National University and Hospital, Jinju 52727, Republic of Korea * Author to whom correspondence should be addressed. Int. J. Mol. Sci.
Contribution of clinical information to the predictive performance of plasma β-amyloid levels for amyloid PET positivity
Min Young Chun1, Hyemin Jang1*, Duk L. Na1, Hee Jin Kim1, Jun Pyo Kim1, José Antonio Allué2, Leticia Sarasa2, Sergio Castillo2, María Pascual-Lucas2 and Sang Won Seo1* 1Samsung Medical Center, Sungkyunkwan University, Republic of Korea 2Araclon Biotech, Spain Provisionally accepted: The final, formatted version of the article will be published soon. Background: Early detection of β-amyloid (Aβ) accumulation, a major biomarker for Alzheimer's disease (AD), has become important.
Clinical outcomes of increased focal amyloid uptake in individuals with subthreshold global amyloid levels
Jaeho Kim1, 2, Yeong Sim Choe1, Yuhyun Park1, Yeshin Kim3, Jun Pyo Kim1, Hyemin Jang1, Hee Jin Kim1, Duk L Na1, Soo Jin Cho2, Seung Hwan Moon1* and Sang Won Seo1* 1Samsung Medical Center, Sungkyunkwan University, Republic of Korea 2College of Medicine, Hallym University, Republic of Korea 3Kangwon National University Hospital, Republic of Korea Provisionally accepted: The final, formatted version of the article will be published soon.
Engineered Lipid Nanoparticles for the Treatment of Pulmonary Fibrosis by Regulating Epithelial‐Mesenchymal Transition in the Lungs
Abstract Pulmonary fibrosis is a chronic and irreversible lung disease with limited therapeutic regimens. Advances in elucidating the pathophysiological mechanism and discovering novel therapeutic interventions are still in urgent need. Here, the engineered lipid nanoparticles (LNPs) are developed for delivering RNA therapeutics to the lungs.
Unified framework for brain connectivity-based biomarkers in neurodegenerative disorders
1. Introduction The brain is composed of structurally and functionally intertwined neurons. This pattern of interconnected neurons can be disrupted or reinforced by the progression of neurodegenerative disorders (Zhan et al., 2016; Lee et al., 2021b; Schumacher et al., 2021; Caravaglios et al., 2022).
Dietary methyl donor nutrients, DNA mismatch repair polymorphisms, and risk of colorectal cancer based on microsatellite instability status - European Journal of Nutrition
Abstract Purpose Colorectal cancer (CRC) is a heterogeneous disease caused by complex interplay among the diet, the environment, and genetics involving numerous molecules and pathological pathways. This study aimed to determine whether methyl donor nutrients are associated with CRC and how these associations are altered by DNA mismatch repair (MMR) genes. Methods In total, 626 cases and 838 age- and sex-matched controls were recruited for this case-control study.
Relationships between educational attainment, hypertension, and amyloid negative subcortical vascular dementia: The brain-battering hypothesis
Introduction Alzheimer's disease dementia (ADD), characterized by amyloid-beta (Aβ), and subcortical vascular dementia (SVaD), indicated by extensive white matter hyperintensities (WMH), are the two most common causes of dementia. Low educational attainment has been regarded as a risk factor for these two types of dementia (Katzman, 1993; Caamaño-Isorna et al., 2006; Sharp and Gatz, 2011). As one of the supporting hypotheses, the brain-battering hypothesis was suggested (Del Ser et al., 1999).
The interaction between glycemic index, glycemic load, and the genetic variant ADIPOQ T45G (rs2241766) in the risk of colorectal cancer: a case–control study in a Korean population - European Journal of Nutrition
Sung H, Ferlay J, Siegel RL et al (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71:209 Google Scholar Hong S, Won YJ, Lee JJ et al (2021) Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2018. Cancer Res Treat 53:301–315 PubMed PubMed Central Google Scholar World Cancer Research Fund/American Institute for Cancer Research. Report, C. U. P. E.
Hepatocellular carcinoma patients with high circulating cytotoxic T cells and intra-tumoral immune signature benefit from pembrolizumab: results from a single-arm phase 2 trial | Genome Medicine | Full Text
Jung Yong Hong ORCID: orcid.org/0000-0003-1363-93321 na1, Hee Jin Cho2,3 na1, Jason K.
Advanced Search Results
(The Beaver Coat) and by Gerhart Hauptmann
Social Distancing against COVID-19: Implication for the Control of Influenza
Social Distancing against COVID-19: Implication for the Control of Influenza Ji Yun Noh,1,2 Hye Seong,1 Jin Gu Yoon,1 Joon Young Song,1,2 Hee Jin Cheong,1,2 and Woo Joo Kim1,2 1Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. 2Asia Pacific Influenza Institute, Korea University College of Medicine, Seoul, Korea. Address for Correspondence: Hee Jin Cheong, MD, PhD.
Identification of molecular signatures involved in radiation-induced lung fibrosis
Our results using SBRT mouse model demonstrate that non-irradiated neighboring regions had a similar gene expression pattern to the pattern observed in the focally irradiated lung regions. Moreover, visual confirmation and changes in gene expression provide evidence of the development of fibrosis even in non-irradiated neighboring lung regions. The fibrotic changes of the boundary regions were weaker than the focally irradiated area of the lung.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Hee
Contact Hee, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack