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Hyuk Sung

As seen in: Biomed Central (BMC), Aging, TechTrends
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Articles

Blood-based multimodal biomarker models for differentiating early-onset Alzheimer’s disease from frontotemporal dementia: a longitudinal study of early-onset dementia and family members (LEAF) study

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By Hyuk Sung, Hee Jin, Sun Min
| TechTrends
van de Veen D, Bakker C, Peetoom K, Pijnenburg Y, Papma J, de Vugt M et al (2022) Provisional consensus on the nomenclature and operational definition of dementia at a young age, a Delphi study. Int J Geriatr Psychiatry. https://doi.org/10.1002/gps.5691 Article PubMed PubMed Central Google Scholar van de Veen D, Bakker C, Peetoom K, Pijnenburg Y, Papma JM, de Vugt M et al (2021) An integrative literature review on the nomenclature and definition of dementia at a young age.
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Biomarkers and therapeutic strategies targeting microglia in neurodegenerative diseases: current status and future directions - Molecular Neurodegeneration

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By Hyuk Sung, Hee Kyung, Seung Woon Hyun, Hanyang College
| Biomed Central (BMC)
Recent advances have highlighted the crucial role of non-neuronal cells in maintaining the central nervous system’s (CNS) homeostasis. Once considered merely supportive, glial cells are now known to actively contribute to synaptic remodeling, CNS immunity, and the integrity of the blood–brain barrier (BBB) [1,2,3].
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Comparison of plasma p-tau217 and p-tau181 in predicting amyloid positivity and prognosis among Korean memory clinic patients - Scientific Reports

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By Seong Hye, Jee Hyang, Hyuk Sung, Myung Hoon
| link.springer.com
Abstract We investigated plasma phosphorylated tau217 (p-tau217) and p-tau181 efficacy in predicting positive amyloid positron emission tomography (PET) results and cognitive stage transitions. Plasma p-tau217 and p-tau181 were measured in participants who were cognitively unimpaired (CU, n = 121), had mild cognitive impairment (n = 102), or dementia (n = 75) from two independent cohorts (Cohort 1: KBASE-V and Cohort 2: Asan) who underwent amyloid PET.
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