Heebal Kim

1 Introduction Domestication has profoundly shaped the genomes of livestock species, producing lineages that reflect both human-mediated selection and adaptation to local environments (Larson and Fuller 2014). The domestic pig (Sus scrofa domesticus), in particular, has a long history of domestication across multiple regions, where breeds have been moulded by local environments, agricultural practices, cultural preferences, and socioeconomic demands (Larson et al. 2005).

Abstract With the rapid advancements in genome sequencing technologies, microbial genome data has exponentially increased, making it essential to continuously update dataset for accurate microbial identification and classification. We present the development of Microbial Identification using rRNA Operon Region (MIrROR) release 02, an expanded dataset based on 1,690,470 genomes (1,674,514 bacterial and 15,956 archaeal) sourced from NCBI.

Abstract Lung cancer is the leading cause of cancer-related mortality worldwide, emphasizing the need for innovative therapeutic strategies. This study utilized immunoinformatics and structural bioinformatics approaches to design and evaluate a multi-epitope vaccine targeting pyroptosis-associated antigens (CARD8, NAIP, NLRP1, and NLRP3), which are implicated in lung cancer immunology.