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Herta Flor

As seen in: Color Research & Application, Nature, Nature Reviews Neurology, MDPI, PNAS, Medscape, Neurology, eLife
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Articles

Model-based analysis of stop-signal data reveals robust neural and clinical correlates of evidence accumulation but not inhibition

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By Yihe Weng, Rory Boyle, Chi Tak Lee, Declan Quinn, Lili Zhang, Tobias Banaschewski, Arun Bokde, Sylvane Desrivières, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Rüdiger Brühl, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Jane McGrath, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Nathalie E. Holz, Sarah Hohmann, Michael N. Smolka, Nilakshi Vaidya, Gunter Schumann, Henrik Walter, Alexander Weigard, Robert Whelan, IMAGEN Consortium, Clodagh Earley, Maike Splittgerber, Luisa Franzen
| Nature Verified
Abstract Poor inhibitory control and decision-making are often considered as risks for substance use and other adverse psychiatric outcomes. The Stop-Signal Task (SST) is a widely used protocol, from which inhibitory control is indexed by stop signal reaction time (SSRT). However, heretofore models of SSRT may be too simplistic to capture complex processes underlying task performance.
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Bullying victimization and brain development: a longitudinal structural magnetic resonance imaging study from adolescence to early adulthood

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By Michael Connaughton, Orla Mitchell, Emer Cullen, Michael O’Connor, Tobias Banaschewski, Gareth Barker, Arun Bokde, Rüdiger Brühl, Sylvane Desrivières, Herta Flor, Hugh Garavan, Penny Gowland, Antoine Grigis, Andreas Heinz, Herve Lemaitre, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Michael N. Smolka, Sarah Hohmann, Nathalie E. Holz, Nilakshi Vaidya, Henrik Walter, Gunter Schumann, Robert Whelan, Darren W. Roddy
| Nature Verified
Abstract This study investigated associations between bullying victimization and brain development using longitudinal structural MRI data from the IMAGEN cohort (n = 2094; 1009 females) across three time points (∼14, ∼19, and ∼22 years).
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A longitudinal DNA methylation atlas and its link to brain structure and mental health

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By Di Chen, Xinyang Yu, Wei Cheng, Linbo Wang, Shitong Xiang, Wei Zhang, Tobias Banaschewski, Arun Bokde, Herta Flor, Antoine Grigis, Hugh Garavan, Penny Gowland, Andreas Heinz, Rüdiger Brühl, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Herve Lemaitre, Tomas Paus, Luise Poustka, Sarah Hohmann, Nathalie E. Holz, Michael N. Smolka, Nilakshi Vaidya, Henrik Walter, Robert Whelan, Jianfeng Feng, Paul Thompson, Gunter Schumann, Tianye Jia, Sylvane Desrivières, Christian Bäuchl
| Nature Verified
Abstract Epigenetic mechanisms are thought to contribute to neurodevelopmental vulnerability for psychiatric disorders, yet longitudinal evidence linking DNA methylation (DNAm) to brain maturation and psychopathology is limited. Using epigenome-wide DNAm (372,582 CpGs) and whole-brain structural MRI data from the IMAGEN cohort (n = 506, ages 14–19), we identified 18 co-regulated DNAm clusters, ten enriched for brain-expressed genes involved in neuronal development and signalling.
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