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1 Introduction Diabetic foot (DF) is defined as wounds that manifest on the feet of individuals suffering from type 1 or type 2 diabetes (1). It is typified by infections, ulcers, and/or deep - tissue damage stemming from peripheral neuropathy and vascular complications in the lower limbs of diabetic patients. The pathogenesis of DF is intricate and multi-factorial, encompassing interrelated mechanisms like infection, micro-and macrovascular diseases, and neurological impairment (2).
Abstract Introduction: This study employed high-throughput sequencing to analyze the diversity of vaginal microbiota in healthy women of reproductive age, thereby establishing a foundational dataset that may inform future forensic applications such as individual identification. Methods: A cohort of 100 healthy reproductive-age women meeting the inclusion criteria was enrolled.
Abstract Background Sepsis-induced acute kidney injury (S-AKI) is a form of acute renal failure resulting from a systemic inflammatory response triggered by infection, and has emerged as a significant public health challenge. Prior studies have demonstrated that artesunate (ART) exerts therapeutic effects on S-AKI by mitigating inflammation and oxidative stress. However, the precise regulatory mechanisms remain to be fully elucidated.
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