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Metabolomics identifies chenodeoxycholic acid as a protective factor in diabetic foot ulcers
1 Introduction Diabetic foot (DF) is defined as wounds that manifest on the feet of individuals suffering from type 1 or type 2 diabetes (1). It is typified by infections, ulcers, and/or deep - tissue damage stemming from peripheral neuropathy and vascular complications in the lower limbs of diabetic patients. The pathogenesis of DF is intricate and multi-factorial, encompassing interrelated mechanisms like infection, micro-and macrovascular diseases, and neurological impairment (2).
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