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Hila Rotbard

As seen in: Cell Press
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Articles

Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle

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By Aviezer Silverman, Raneem Nashef, Reut Wasserman, Tamar Noy, Susan Born, Tianyou Yao, Yuncong Geng, Hila Rotbard, Adi Levkowitz, Yotam Kaufman, Ido Golding, Sahar Melamed
| Cell Press Verified
Keywords sRNA RIL-seq lambda phage anti-phage replication regulation RNA-RNA interactions Hfq phage-host interactions Introduction Bacteriophage (phage) research over the past century has driven major biological discoveries in core molecular processes and bacterial defense systems such as CRISPR-Cas, DISARM (Defence Island System Associated with Restriction-Modification), and restriction enzymes.1,2 Phages are the most abundant genetic entities on Earth (≈1031)3 and shape bacterial evolution...
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