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Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Urea cycle disorders include citrullinemia type I (CTLN1), which is caused by pathogenic variants in the argininosuccinate synthetase 1 (ASS1) gene.
Abstract Lipid nanoparticle (LNP)-encapsulated nucleoside-modified mRNA vaccines elicit robust CD4+ T cell responses, yet the mechanisms underlying this T cell priming remain unknown. Antigens presented to CD4+ T cells on major histocompatibility complex class II (MHC II) are traditionally acquired by antigen presenting cells (APCs) from extracellular sources.
ArticleOnline nowOpen access 1Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA 2Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA 3Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA 4Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy 5Department of Pathology, University of Massachusetts Chan...
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