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Hiroto Kuwabara on Muck Rack

Hiroto Kuwabara

As seen in: Cell Press, EJNMMI Research
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Articles

Head to head comparison of two PET/CT imaging agents, [18F]D3FSP ([18F]P16-129) and [18F]AV45, in patients with alzheimer’s disease - EJNMMI Research

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By David L. Alexoff, Dean F. Wong, Hiroto Kuwabara, Robert F. Dannals, Karl Ploessl, Hank F. Kung
| EJNMMI Research Verified
Eight subjects with clinically diagnosed AD were enrolled (mean age: 61.1 ± 10.0 years [SD], range: 50–77; 5 males, 3 females). The average Mini-Mental State Examination (MMSE) score was 21 ± 4 [SD], with a range of 15–26. The results of the plasma metabolite assay are summarized in Fig. 2 below. The was no difference in parent (left panel) or the des-methyl metabolite (right panel) fractions for [18F]D3FSP and [18F]AV-45 over the time course of imaging.
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The Role of Dopamine in Value-Based Attentional Orienting

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By Brian Anderson, Johns Hopkins, Dean F. Wong, Hiroto Kuwabara
| Cell Press Verified
Highlights • We examined the neural correlates of value-based attention using PET • Previously reward-associated stimuli involuntary captured attention as distractors • Such attentional capture was predicted by dopamine release in the dorsal striatum • Our findings elucidate the neurochemical basis of value-based distraction Summary , , 3 Anderson B.A. Yantis S. Value-driven attentional and oculomotor capture during goal-directed, unconstrained viewing. Atten. Percept. Psychophys.
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