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Hiroyuki Matsubara

As seen in: Wiley Online Library, Cell Press
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Articles

Emerging landscape of KRAS inhibitors in cancer treatment

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By Jakob M. Riedl, Hiroyuki Matsubara, Reid McNeil, Parasvi S. Patel, Doga C. Gulhan, Ryan B. Corcoran, Ferran Fece de la Cruz
| Cell Press Verified
Keywords KRAS KRAS inhibitor KRAS G12C drug resistance non-small cell lung cancer colorectal cancer pancreatic cancer Introduction Mutations in the RAS gene family (KRAS, NRAS, and HRAS) occur in approximately 20% of human cancers, affecting an estimated 3.4 million new patients worldwide each year.1 RAS proteins are ubiquitously expressed in almost all cell types, with KRAS representing the most abundant isoform.2 Consistently, in vivo studies have shown that full knockout of the KRAS gene...
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An activity recognition system at home based on illuminance sensors

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By Hiroyuki Matsubara
| Wiley Online Library Verified
REFERENCES 1. About special issue on developing technologies for situational awareness to ensure human safety. Syst Contr Inf. 2005; 49(4): 147. (in Japanese). 2, , , , , . Safety confirmation of elderly people by monitoring home electric appliances using magnetic resistance sensor. J IIAE. 2015; 3(2): 42-47. (in Japanese). 3, , , , , . Estimation of the number of walking people in staircases using infrared human detection sensors. J Archit Plan (Trans AIJ). 2022; 87(799): 1699-1707. (in Japanese).
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