Hongbo Yin

Keywords cell-surface RNA RNA-binding protein ribonucleoprotein heparan sulfate Toll-like receptor 7 proximity labeling RNA-protein crosslinking genome-wide screening quantitative proteomics immune receptor Get full text access Log in, subscribe or purchase for full access. References 1. Block, K.F. ∙ Puerta-Fernandez, E. ∙ Wallace, J.G. ... Association of OLE RNA with bacterial membranes via an RNA-protein interaction Mol. Microbiol. 2011; 79:21-34 2. Flynn, R.A. ∙ Pedram, K. ∙ Malaker, S.A. ...

Abstract Recent discoveries have shown the presence of RNA molecules on the cell surface, defying the traditional view that RNA only functions intracellularly. However, it is not well understood how cell-surface RNA (csRNA) is stably present on the plasma membrane and what functions it performs. We answer the pressing questions in the emerging field by taking integrated omic-wide approaches and multiple orthogonal validatory methods.