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FSHR and LHR functional compensation reveals the mechanism and treatment of Ovarian Hyperstimulation Syndrome
Abstract Gain-of-function mutations in the human follicle-stimulating hormone receptor (FSHR) cause spontaneous ovarian hyperstimulation syndrome (OHSS), a serious reproductive disorder. However, the molecular physiology and treatment options for OHSS remain elusive. Notably, estrildid finches naturally carry an FSHR variant (Thr449Ala) analogous to the pathogenic mutation in humans yet are resistant to OHSS.
Clinical Approaches for the Management of Skin Cancer: A Review of Current Progress in Diagnosis, Treatment, and Prognosis for Patients with Melanoma
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B cell c-Maf signaling promotes tumor progression in animal models of pancreatic cancer and melanoma
Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways. Melanoma Immune modulatory B cell Tumor microenvironment - TME WHAT IS ALREADY KNOWN ON THIS TOPIC The net effect of B cells on tumor immunity depends on the balance of various B cell subtypes.
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